CAS 29976-53-2

1-(Ethoxycarbonyl)-4-piperidone

Description:

1-(Ethoxycarbonyl)-4-piperidone, with the CAS number 29976-53-2, is a chemical compound characterized by its piperidone structure, which includes a piperidine ring with a carbonyl group and an ethoxycarbonyl substituent. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. It is soluble in organic solvents such as ethanol and dichloromethane but has limited solubility in water. The presence of the ethoxycarbonyl group contributes to its reactivity, making it useful in various organic synthesis applications, particularly in the preparation of pharmaceuticals and agrochemicals. The compound may exhibit moderate toxicity, and appropriate safety measures should be taken when handling it. Its chemical properties, including boiling point, melting point, and specific reactivity, can vary based on the conditions and purity of the sample. Overall, 1-(Ethoxycarbonyl)-4-piperidone is a versatile intermediate in synthetic organic chemistry.

Formula: C₈H₁₃NO₃

InChI: InChI=1S/C8H13NO3/c1-2-12-8(11)9-5-3-7(10)4-6-9/h2-6H2,1H3

InChI key: InChIKey=LUBGFMZTGFXIIN-UHFFFAOYSA-N

SMILES: C(OCC)(=O)N1CCC(=O)CC1

Synonyms:

• 1-(Carboethoxy)-4-piperidinone
• 1-(Carboethoxy)-4-piperidone
• 1-Carbethoxy-4-Piperidone
• 1-Carbethoxypiperidin-4-one
• 1-Ethoxycarbonyl-4-oxopiperidine
• 1-Ethoxycarbonyl-4-piperidinone
• 1-Ethoxycarbonyl-4-piperidone
• 1-Piperidinecarboxylic Acid, 4-Oxo-, Ethyl Ester
• 4-Oxo-1-piperidinecarboxylic acid ethyl ester
• 4-Oxo-Piperidine-1-Carboxylic Acid Ethyl Ester
• 4-Piperidone-1-Carboxylic Acid Ethyl Ester
• 4-Piperidone-N-Carboxylic Acid Ethyl Ester
• Aurora Ka-3057
• Ethyl 4-Oxopiperidine-1-Carboxylate
• Ethyl 4-Piperidone-1-Carboxylate
• Ethyl 4-Piperidone-N-Carboxylate
• Ethyl 4-oxo-1-piperidinecarboxylate
• N-Carbethoxy-4-piperidinone
• N-Carbithoxy-4-Piperidone
• N-Carboethoxy-4-piperidone
• N-Ethoxycarbonyl-4-Piperidone
• N-Ethoxycarbonyl-4-piperidinone

1-Ethoxycarbonyl-4-piperidone

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Purity: >97.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 171.20

Ref: 3B-E0403

LORATADINE IMPURITY H CRS

CAS: 29976-53-2

LORATADINE IMPURITY H CRS

Formula: C₈H₁₃NO₃

Molecular weight: 171.1937

Ref: 41-Y0000605

N-Carbethoxy-4-piperidone

CAS: 29976-53-2

N-Carbethoxy-4-piperidone is an aminopyrimidine derivative, compositions containing them and there served as pharmaceuticals.

Formula: C₈H₁₃NO₃

Purity: 97.82%

Color and Shape: Less Liquid Colorless Liquid

Molecular weight: 171.19

Ref: TM-T1340

Ethyl 4-oxopiperidine-1-carboxylate

CAS: 29976-53-2

Ethyl 4-oxopiperidine-1-carboxylate

Purity: 98%

Molecular weight: 171.19g/mol

Ref: 54-OR6942

N-Carbethoxy-4-piperidone

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Molecular weight: 171.20

Ref: 7W-GK4888

Ethyl 4-Oxopiperidine-1-carboxylate

Controlled Product

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Color and Shape: Neat

Molecular weight: 171.19

Ref: 86-MM0257.07

N-Carbethoxy-4-piperidone

Controlled Product

CAS: 29976-53-2

Impurity Loratadine EP Impurity H
Applications N-Carbethoxy-4-piperidone (Loratadine EP Impurity H) is used in the preparation of 3-hydrazinopyridazines as antihypertensive agents as well as γ-carboline derivatives as potential serotonergic agents. N-Carbethoxy-4-piperidone is also an impurity of Loratadine (L469575).
References Schenker, E. et al.: Arsneim.-Forsch., 29, 1835 (1979); El-Kader, A. et al.: Mans. J. Pharm. Sci., 6, 1 (1989); Albu, M. et al.: J. Liq. Chrom. Rel. Technol., 32, 2569 (2009);

Formula: C₈H₁₃NO₃

Color and Shape: Neat

Molecular weight: 171.19

Ref: TR-C176120

Loratadine EP Impurity H

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Molecular weight: 171.19

Ref: ST-EA-CP-L5008

Ethyl 4-piperidone-N-carboxylate

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 171.196

Ref: 10-F022135

4-Oxo-1-piperidinecarboxylic acid ethyl ester

Controlled Product

CAS: 29976-53-2

4-Oxo-1-piperidinecarboxylic acid ethyl ester is an antimicrobial agent that belongs to the group of unsaturated ketones. It has been shown to have clinical activity against gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis and Streptococcus pneumoniae, as well as Candida albicans. It also exhibits significant antiinflammatory activity in mice with chronic inflammation induced by carrageenan or LPS. 4-Oxo-1-piperidinecarboxylic acid ethyl ester inhibits the enzyme dpp-4, which is involved in the production of amyloid beta peptides and type II diabetes. This compound was also shown to possess anticholinesterase activity in vitro.

Formula: C₈H₁₃NO₃

Purity: Min. 95%

Molecular weight: 171.19 g/mol

Ref: 3D-FO29358

N-Carbethoxy-4-piperidone

CAS: 29976-53-2

Formula: C₈H₁₃NO₃

Purity: 98%

Color and Shape: Liquid

Molecular weight: 171.1937

Ref: IN-DA0035DC