CAS 299912-61-1

Erlotinib Impurity 18 HCl

CAS: 299912-61-1

Formula: C₂₂H₂₇N₃O₄·HCl

Molecular weight: 397.48 36.46

Ref: 4Z-E-2836

Tetrahydro erlotinib

CAS: 299912-61-1

Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.

Formula: C₂₂H₂₇N₃O₄

Purity: Min. 95%

Molecular weight: 397.5 g/mol

Ref: 3D-ZLA91261