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CAS 2999794-78-2

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    NNRT-IN-2

    CAS:
    NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1].
    Formula:C19H14F3N5O3
    Molecular weight:417.34

    Ref: TM-T87027