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CAS 30042-37-6

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Lankamycin

Description:
Lankamycin is a naturally occurring antibiotic that belongs to the class of compounds known as macrolides. It is produced by the fermentation of certain strains of Streptomyces bacteria. Lankamycin exhibits antibacterial properties, particularly against Gram-positive bacteria, making it valuable in the field of medicinal chemistry and pharmacology. The compound is characterized by its large lactone ring structure, which is typical of macrolides, and it contains various functional groups that contribute to its biological activity. Lankamycin's mechanism of action primarily involves the inhibition of protein synthesis in bacterial cells, thereby preventing their growth and replication. Additionally, it has been studied for its potential use in treating various infections, although its clinical application may be limited compared to other antibiotics. As with many antibiotics, the emergence of resistance is a concern, necessitating ongoing research into its efficacy and potential modifications to enhance its therapeutic profile. Overall, Lankamycin represents an important compound in the study of antibiotic development and microbial resistance.
Formula:C42H72O16
InChI:InChI=1S/C42H72O16/c1-19-17-41(12,49)37(47)24(6)35(54-28(10)44)23(5)34(21(3)26(8)43)57-39(48)25(7)36(22(4)33(19)58-40-32(46)30(50-14)16-20(2)52-40)56-31-18-42(13,51-15)38(27(9)53-31)55-29(11)45/h19-27,30-36,38,40,43,46,49H,16-18H2,1-15H3/t19-,20+,21-,22+,23-,24+,25+,26-,27-,30-,31-,32+,33-,34+,35-,36-,38+,40-,41-,42+/m0/s1
InChI key:InChIKey=JQMACDQCTNFQMM-QAOHEUSVSA-N
SMILES:O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@H](OC(C)=O)[C@H](C)O2)[C@@H](C)C(=O)O[C@]([C@H]([C@H](C)O)C)([C@H](C)[C@H](OC(C)=O)[C@@H](C)C(=O)[C@@](C)(O)C[C@@H]1C)[H])[C@H]3[C@H](O)[C@@H](OC)C[C@@H](C)O3
Synonyms:
  • Oxacyclotetradecane-2,10-dione, 4-[(4-O-acetyl-2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-xylo-hexopyranosyl)oxy]-12-(acetyloxy)-6-[(4,6-dideoxy-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-9-hydroxy-14-[(1S,2S)-2-hydroxy-1-methylpropyl]-3,5,7,9,11,13-hexamethyl-, (3R,4S,5R,6S,7S,9S,11R,12S,13S,14R)-
  • Oxacyclotetradecane, lankamycin deriv.
  • Lankamycin
  • (3R,4S,5R,6S,7S,9S,11R,12S,13S,14R)-4-[(4-O-Acetyl-2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-xylo-hexopyranosyl)oxy]-12-(acetyloxy)-6-[(4,6-dideoxy-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-9-hydroxy-14-[(1S,2S)-2-hydroxy-1-methylpropyl]-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione
  • Oxacyclotetradecane-2,10-dione, 4-[(4-O-acetyl-2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-xylo-hexopyranosyl)oxy]-12-(acetyloxy)-6-[(4,6-dideoxy-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-9-hydroxy-14-(2-hydroxy-1-methylpropyl)-3,5,7,9,11,13-hexamethyl-, [3R-[3R*,4S*,5R*,6S*,7S*,9S*,11R*,12S*,13S*,14R*(1S*,2S*)]]-
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Found 1 products.
  • Lankamycin

    CAS:
    <p>Lankamycin is a macrolide antibiotic from various strains of Streptomyces. It may have significant activity against some Gram positive bacteria.</p>
    Formula:C42H72O16
    Purity:98%
    Color and Shape:Solid
    Molecular weight:833.01