CAS 300552-09-4

2-Pyrimidinemethanol, 4,4′-[(2R,6S)-2,6-dimethyl-1,4-piperazinediyl]bis[α-methyl-, (α1S,α4R)-

Description:

2-Pyrimidinemethanol, 4,4′-[(2R,6S)-2,6-dimethyl-1,4-piperazinediyl]bis[α-methyl-, (α1S,α4R)- is a complex organic compound characterized by its unique structural features, including a pyrimidine ring and a piperazine moiety. This compound typically exhibits properties associated with both its aromatic and aliphatic components, such as moderate solubility in polar solvents due to the presence of hydroxyl and amine functional groups. The stereochemistry indicated by the (2R,6S) and (α1S,α4R) descriptors suggests specific spatial arrangements that can influence its biological activity and interactions with other molecules. It may participate in hydrogen bonding due to the hydroxyl group, enhancing its reactivity and potential as a ligand in biochemical applications. Additionally, the presence of methyl groups can affect its lipophilicity and overall stability. Such compounds are often studied for their potential pharmacological properties, including their role as enzyme inhibitors or in receptor binding, making them of interest in medicinal chemistry and drug development.

Formula: C₁₈H₂₆N₆O₂

Synonyms:

• 2-Pyrimidinemethanol, 4,4′-[(2R,6S)-2,6-dimethyl-1,4-piperazinediyl]bis[α-methyl-, (α1S,α4R)-

(6S)-CP-470711

CAS: 300552-09-4

(6S)-CP-470711 (Compound 8) acts as an inhibitor of sorbitol dehydrogenase (SDH) in both humans and rats, exhibiting inhibitory concentrations (IC50) of 19 nM and 27 nM, respectively. Additionally, (6S)-CP-470711 has been shown to ameliorate diabetes in rats induced by Streptozotocin.

Formula: C₁₈H₂₆N₆O₂

Color and Shape: Solid

Molecular weight: 358.44

Ref: TM-T201689