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CAS 3005979-40-5

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  • AR antagonist 11

    CAS:
    <p>AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM). Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM). This compound is applicable in prostate cancer (PCa) research.</p>
    Formula:C20H17ClN2O
    Color and Shape:Solid
    Molecular weight:336.815