CAS 300801-03-0

[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)

Description:

The chemical substance known as "[glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)" with CAS number 300801-03-0 is a coordination complex that features a copper ion coordinated to a peptide ligand derived from glycine, histidine, and lysine. This compound exhibits characteristics typical of metal-peptide complexes, including potential biological activity due to the presence of amino acid residues that can interact with biological systems. The copper ion in this complex can participate in redox reactions, making it relevant in biochemical processes. The acetate moiety suggests that the compound may have solubility in polar solvents, which is important for its potential applications in biological or pharmaceutical contexts. Additionally, the specific coordination environment around the copper ion can influence the stability, reactivity, and overall properties of the complex. Such compounds are often studied for their roles in metalloproteins, enzyme mimetics, and therapeutic agents, particularly in the context of metal ion homeostasis and oxidative stress.

Formula: C₁₆H₂₅CuN₆O₆

Synonyms:

• Glycyl-L-Histidyl-L-Lysine Copper acetate(1:1)
• (2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoate
• GHK-Cuacetat
• [glycyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-Copper, monoacetate (9CI)
• GHK-Cu (acetate)

GHK-Cu

CAS: 300801-03-0

Formula: C₁₆H₂₆CuN₆O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 461.9602

Ref: IN-DA01DNDG

N2-(N-glycyl-L-histidyl)-L-Lysine, copper complex,acetate

CAS: 300801-03-0

N2-(N-glycyl-L-histidyl)-L-Lysine, copper complex,acetate

Purity: 98%

Molecular weight: 461.97g/mol

Ref: 54-IN12977

GHK-Cu acetate

CAS: 300801-03-0

GHK-Cu is a copper complex of GHK (glycyl-L-histidyl-L-lysine) that has been shown to have many useful properties. It has been used as a building block for the preparation of complex compounds such as metal chelates, peptides, and polymers. In addition, GHK-Cu acetate can be used as a reagent in research. This compound is useful in the synthesis of high quality chemicals, such as fine chemicals and pharmaceuticals.

Formula: C₁₆H₂₆CuN₆O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 462 g/mol

Ref: 3D-FG180051

GHK-Cu acetate

CAS: 300801-03-0

GHK-Cu acetate, a complex of the tripeptide Gly-His-Lys and a copper(II) ion, exhibits wound healing and anti-inflammatory properties. It enhances fibroblast proliferation, collagen production, and the release of pro-matrix metalloproteinase-2 (MMP-2) and glycosaminoglycans (GAGs), while also increasing decorin expression in rat wound tissue. Furthermore, at a concentration of 10 µM, it reduces levels of reactive oxygen species (ROS), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) in LPS-stimulated RAW 264.7 cells. Additionally, GHK-Cu at 10 µg/g mitigates LPS-induced reductions in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels, decreases the accumulation of cells and total protein in bronchoalveolar lavage fluid (BALF), and thus, attenuates acute lung injury in mice.

Formula: C₁₄H₂₂CuN₆O₄C₂H₄O₂

Color and Shape: Solid

Molecular weight: 462

Ref: TM-T85063