CAS 300816-15-3

6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

Description:

6-Methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, with CAS number 300816-15-3, is a complex organic compound characterized by its unique spirocyclic structure, which combines elements of benzoxazine and piperidine. This compound features a 1,3-oxazole moiety, contributing to its potential biological activity. The presence of multiple functional groups, including a methyl group and a phenyl ring, suggests that it may exhibit diverse chemical reactivity and potential interactions with biological targets. Its spiro configuration indicates a rigid molecular framework, which can influence its pharmacokinetic properties, such as solubility and permeability. The compound's synthesis and characterization would typically involve advanced organic chemistry techniques, and its potential applications could span medicinal chemistry, particularly in drug development, due to the presence of pharmacophoric elements. Further studies would be necessary to elucidate its specific biological activities and therapeutic potential.

Formula: C₂₅H₂₇N₃O₃

InChI: InChI=1/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29)

SMILES: Cc1ccc2c(c1)C1(CCN(CCc3c(C)oc(c4ccccc4)n3)CC1)OC(=N2)O

Synonyms:

• Spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-
• 6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
• 6-Methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one

CAS: 300816-15-3

Formula: C₂₅H₂₇N₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 417.5002

Ref: IN-DA0035KM

RS 504393

CAS: 300816-15-3

RS 504393

Purity: 98%

Molecular weight: 417.5g/mol

Ref: 54-OR1023058

RS 504393

CAS: 300816-15-3

RS 504393

Purity: ≥98%

Molecular weight: 417.5g/mol

Ref: 54-BUP04801

RS 504393

CAS: 300816-15-3

RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).

Formula: C₂₅H₂₇N₃O₃

Purity: 98.64% - 99.62%

Color and Shape: Solid

Molecular weight: 417.5

Ref: TM-T5384

RS 504393

Controlled Product

CAS: 300816-15-3

Formula: C₂₅H₂₇N₃O₃

Color and Shape: Neat

Molecular weight: 417.5

Ref: TR-R701020

RS 504393

CAS: 300816-15-3

RS 504393 is a potent and selective antagonist of Toll-like receptor 4 (TLR4) that has been shown to inhibit the production of proinflammatory cytokines, chemokines, and nitric oxide. RS 504393 has been shown to be effective in the treatment of bone cancer, as well as in the prevention of renal injury due to tubulointerstitial damage. This drug has also been shown to have anti-inflammatory effects in a model system through inhibition of chemokine production. RS 504393 is an ester hydrochloride salt that binds with high affinity to TLR4 receptors, inhibiting receptor activity by preventing ligand binding.

Formula: C₂₅H₂₇N₃O₃

Purity: Min. 95%

Molecular weight: 417.5 g/mol

Ref: 3D-AMA81615