CAS 300817-68-9

BH3I-1

CAS: 300817-68-9

BH3I-1 (BHI1) is a Bcl-2 antagonist.

Formula: C₁₅H₁₄BrNO₃S₂

Purity: 97.6% - 98.2%

Color and Shape: Solid

Molecular weight: 400.31

Ref: TM-T1493

BH3I-1

CAS: 300817-68-9

Formula: C₁₅H₁₄BrNO₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.3106

Ref: IN-DA00BF78

2-(5-(4-Bromobenzylidene)-4-Oxo-2-Thioxothiazolidin-3-Yl)-3-Methylbutanoic Acid

CAS: 300817-68-9

2-(5-(4-Bromobenzylidene)-4-Oxo-2-Thioxothiazolidin-3-Yl)-3-Methylbutanoic Acid

Purity: 98%

Molecular weight: 400.31g/mol

Ref: 54-OR1009784

BH3I-1

CAS: 300817-68-9

BH3I-1

Purity: ≥95%

Molecular weight: 400.31g/mol

Ref: 54-BUP01990

BH3I-1

CAS: 300817-68-9

Formula: C₁₅H₁₄BrNS₂O₃

Molecular weight: 400.31

Ref: 7W-GL0660

BH3I-1

CAS: 300817-68-9

BH3I-1 is a potent inhibitor of the Bcl-2 family of proteins that are involved in apoptosis. It has been shown to be effective against a range of tumor cell lines, including prostate cancer cells and human leukemia cells. The molecular target for BH3I-1 is the mitochondrial membrane potential, which is required for the production of ATP and maintenance of cellular homeostasis. In a panel of radiation-resistant tumor cell lines, BH3I-1 potently inhibited growth and induced morphological changes. This molecule also inhibits dimorphic fungi such as Candida glabrata, which can cause opportunistic infections in immunocompromised patients.

Formula: C₁₅H₁₄BrNS₂O₃

Purity: Min. 95%

Molecular weight: 400.31 g/mol

Ref: 3D-AMA81768