The chemical substance known as "σ1 Receptor/μ Opioid receptor modulator 2," with the CAS number 3009018-61-2, is a compound that exhibits dual activity by modulating both sigma-1 receptors and mu-opioid receptors. Sigma-1 receptors are implicated in various neuroprotective and neuropsychiatric processes, while mu-opioid receptors are primarily associated with pain relief and the modulation of mood. This compound may demonstrate potential therapeutic applications in pain management, mood disorders, and neuroprotection due to its ability to influence these two receptor systems. The modulation of these receptors can lead to a range of biological effects, including analgesia, sedation, and possibly the reduction of opioid tolerance. Additionally, the compound's pharmacological profile may suggest a lower risk of addiction compared to traditional opioids, making it a subject of interest in drug development. However, detailed studies on its efficacy, safety, and mechanism of action are essential to fully understand its potential therapeutic benefits and risks.

σ1 Receptor/μ Opioid receptor modulator 2

3009018-61-2: The chemical substance known as "σ1 Receptor/μ Opioid receptor modulator 2," with the CAS number 3009018-61-2, is a compound that exhibits dual activity by modulating both sigma-1 receptors and mu-opioid receptors. Sigma-1 receptors are implicated in various neuroprotective and neuropsychiatric processes, while mu-opioid receptors are primarily associated with pain relief and the modulation of mood. This compound may demonstrate potential therapeutic applications in pain management, mood disorders, and neuroprotection due to its ability to influence these two receptor systems. The modulation of these receptors can lead to a range of biological effects, including analgesia, sedation, and possibly the reduction of opioid tolerance. Additionally, the compound's pharmacological profile may suggest a lower risk of addiction compared to traditional opioids, making it a subject of interest in drug development. However, detailed studies on its efficacy, safety, and mechanism of action are essential to fully understand its potential therapeutic benefits and risks.

Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.

CAS 3009018-61-2

σ1 Receptor/μ Opioid receptor modulator 2

σ1 Receptor/μ Opioid receptor modulator 2

Ref: TM-T208835