1,3-Dimethyl-5-fluorouracil is a synthetic derivative of uracil, characterized by the presence of two methyl groups at the 1 and 3 positions and a fluorine atom at the 5 position of the pyrimidine ring. This compound is classified as an antimetabolite and is primarily studied for its potential use in cancer therapy, particularly in the treatment of various solid tumors. Its mechanism of action involves the inhibition of thymidylate synthase, which is crucial for DNA synthesis and repair, thereby disrupting the proliferation of cancer cells. The compound is typically a white to off-white crystalline solid, and it is soluble in polar solvents. Due to its structural modifications, 1,3-dimethyl-5-fluorouracil exhibits altered pharmacokinetic properties compared to its parent compound, fluorouracil, potentially leading to enhanced efficacy and reduced toxicity. As with many fluorinated compounds, it is important to handle this substance with care, as it may pose health risks if not managed properly.

1,3-dimethyl-5-fluorouracil

3013-92-1: 1,3-Dimethyl-5-fluorouracil is a synthetic derivative of uracil, characterized by the presence of two methyl groups at the 1 and 3 positions and a fluorine atom at the 5 position of the pyrimidine ring. This compound is classified as an antimetabolite and is primarily studied for its potential use in cancer therapy, particularly in the treatment of various solid tumors. Its mechanism of action involves the inhibition of thymidylate synthase, which is crucial for DNA synthesis and repair, thereby disrupting the proliferation of cancer cells. The compound is typically a white to off-white crystalline solid, and it is soluble in polar solvents. Due to its structural modifications, 1,3-dimethyl-5-fluorouracil exhibits altered pharmacokinetic properties compared to its parent compound, fluorouracil, potentially leading to enhanced efficacy and reduced toxicity. As with many fluorinated compounds, it is important to handle this substance with care, as it may pose health risks if not managed properly.

5-Fluoro-1,3-dimethyluracil

5-Fluoro-1,3-Dimethylpyrimidine-2,4(1H,3H)-Dione

CAS 3013-92-1

1,3-dimethyl-5-fluorouracil

5-Fluoro-1,3-dimethyluracil

Ref: IN-DA00BEXJ

5-Fluoro-1,3-Dimethylpyrimidine-2,4(1H,3H)-Dione

Ref: 54-PC109181