α-Glucosidase-IN-43 is a chemical compound that functions as an inhibitor of the enzyme α-glucosidase, which plays a crucial role in carbohydrate metabolism by breaking down complex carbohydrates into simple sugars. This inhibition can be particularly beneficial in managing conditions such as diabetes, as it slows the absorption of glucose from the intestine, thereby helping to regulate blood sugar levels. The compound is characterized by its specific molecular structure, which includes functional groups that interact with the active site of the enzyme, preventing its activity. While detailed physicochemical properties such as solubility, melting point, and stability may vary, compounds of this nature are typically designed to be bioavailable and effective at low concentrations. Research into α-Glucosidase-IN-43 may also explore its pharmacokinetics, potential side effects, and therapeutic applications, particularly in the context of metabolic disorders. As with any pharmaceutical agent, safety and efficacy are paramount, necessitating thorough clinical evaluation before widespread use.

α-Glucosidase-IN-43

3018963-27-1: α-Glucosidase-IN-43 is a chemical compound that functions as an inhibitor of the enzyme α-glucosidase, which plays a crucial role in carbohydrate metabolism by breaking down complex carbohydrates into simple sugars. This inhibition can be particularly beneficial in managing conditions such as diabetes, as it slows the absorption of glucose from the intestine, thereby helping to regulate blood sugar levels. The compound is characterized by its specific molecular structure, which includes functional groups that interact with the active site of the enzyme, preventing its activity. While detailed physicochemical properties such as solubility, melting point, and stability may vary, compounds of this nature are typically designed to be bioavailable and effective at low concentrations. Research into α-Glucosidase-IN-43 may also explore its pharmacokinetics, potential side effects, and therapeutic applications, particularly in the context of metabolic disorders. As with any pharmaceutical agent, safety and efficacy are paramount, necessitating thorough clinical evaluation before widespread use.

<p>α-Glucosidase-IN-43 (compound AS14) is an α-glucosidase inhibitor with an IC50 of 4.32 μM, demonstrating acute blood-glucose-lowering properties. It is safe and effective in vivo, showing no toxicity to normal fibroblasts in mice and can ameliorate diabetes induced by streptozotocin in rats. α-Glucosidase-IN-43 is applicable for research on postprandial hyperglycemia in diabetic patients.</p>

CAS 3018963-27-1

α-Glucosidase-IN-43

α-Glucosidase-IN-43

Ref: TM-T208265