CAS 302-79-4

Retinoic acid

Description:

Retinoic acid, with the CAS number 302-79-4, is a metabolite of vitamin A (retinol) and plays a crucial role in various biological processes, including cell growth, differentiation, and embryonic development. It exists in two primary forms: all-trans-retinoic acid and 13-cis-retinoic acid, each exhibiting distinct biological activities. Retinoic acid is a lipophilic compound, which means it is soluble in organic solvents but has limited solubility in water. It acts primarily through nuclear receptors, influencing gene expression and cellular functions. This compound is essential in dermatology, particularly in the treatment of acne and skin aging, as it promotes cell turnover and reduces hyperkeratinization. Additionally, retinoic acid is involved in the regulation of immune responses and has potential therapeutic applications in cancer treatment, particularly in acute promyelocytic leukemia. However, its use must be carefully monitored due to potential side effects, including teratogenicity and skin irritation. Overall, retinoic acid is a vital compound in both physiological processes and therapeutic applications.

Formula: C₂₀H₂₈O₂

InChI: InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+

InChI key: InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N

SMILES: C(=C/C(=C/C=C/C(=C/C(O)=O)/C)/C)\C=1C(C)(C)CCCC1C

Synonyms:

• (11Cis,13Cis)-7,8-Dihydroretinoic Acid
• (9Cis)-Retinoic Acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid
• 15-Oxidoretinal
• 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
• Aberel
• Acide retinoique
• Agn 100335
• Airol
• Aknoten
• Atra
• Atragen
• Cordes Vas
• Dermairol
• Epi-Aberel
• Eudyna
• N,N'-hexane-1,6-diyldiacetamide
• Nsc 122578
• Nsc 122758
• Renova
• Retacnyl
• Retin A
• Retinoic Acid
• Retinoic acid, all-trans-
• Retionoic Acid
• Ro 1-5488
• Tretin M
• Tretin M, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
• Tretinion
• Tretinoin (Retionoic Acid)
• Tretinoine
• Tretinoino
• Vesanoid
• Vesnaroid
• Vitamin A acid
• Vitamin A acid, all-trans-
• Vitamin A1 acid, all-trans-
• Vitamin A₁ acid, all-trans-
• all-(E)-Retinoic acid
• all-trans-Retinoic acid
• all-trans-Tretinoin
• all-trans-Vitamin A acid
• all-trans-β-Retinoic acid
• trans-Retinoic acid
• β-Retinoic acid
• Tretinoein
• Tretinoin
• AKOS 92103
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOIC ACID
• ALL-TRANS-RETINOIE ACID
• ISOTRETINOIN
• 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2E,4E,6E,8E-NONATETRAENOIC ACID
• RETINOIC ACID ALL TRANS ISOMER
• 13-CIS-RETINOIC ACID
• 9-TRANS-TRETINOIN
• (L)-ISOTRETINOIN
• TRANS VITAMIN A ACID
• RETINOIC ACID, 13-CIS-

Retinoic Acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purity: >93.0%(HPLC)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 300.44

Ref: 3B-R0064

Retinoic acid, 97%

CAS: 302-79-4

Retinoic acid (tretinoin or all-trans-retinoic acid (ATRA)), 302-79-4, is a naturally occuring derivative of retinol which is implicated in cell differentiation. Learn more.

Formula: C₂₀H₂₈O₂

Purity: 97%

Color and Shape: Pale yellow to yellow, Powder or crystalline powder

Molecular weight: 300.44

Ref: 02-044540

TRETINOIN CRS

CAS: 302-79-4

TRETINOIN CRS

Formula: C₂₀H₂₈O₂

Color and Shape: Added Modified

Molecular weight: 300.4351

Ref: 41-T1850000

Tretinoin

CAS: 302-79-4

Tretinoin

Formula: C₂₀H₂₈O₂

Purity: 99.5%

Color and Shape: Yellow

Molecular weight: 300.20893

Ref: 47-1205

Retinoic acid

CAS: 302-79-4

Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.

Formula: C₂₀H₂₈O₂

Purity: 97.21% - 99.6%

Color and Shape: Yellow-Orange Powder

Molecular weight: 300.44

Ref: TM-T1051

Retinoic acid

CAS: 302-79-4

Retinoic acid

Purity: ≥95%

Molecular weight: 300.44g/mol

Ref: 54-BUP14667

Retinoic Acid

CAS: 302-79-4

Retinoic Acid

Formula: C₂₀H₂₈O₂

Purity: 99%

Color and Shape: yellow to amber to dark green crystal or powder

Molecular weight: 300.44g/mol

Ref: 54-OR1014889

Retinoic acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purity: 98.0 - 102.0 % (dried basis)

Color and Shape: Yellow powder

Molecular weight: 300.44

Ref: 7W-GP4026

Tretinoin (Retinoic Acid, Isotretinoin EP Impurity A)

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Molecular weight: 300.44

Ref: 4Z-T-114001

Retinoic acid, USP grade

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purity: (Titration) 97.0 - 103.0 % (dried basis)

Color and Shape: Yellow to light-orange crystalline powder

Molecular weight: 300.44

Ref: 7W-GP2891

Tretinoin-d5 (Retinoic Acid-d5, Isotretinoin EP Impurity A-d5)

CAS: 302-79-4, 78996-15-3

Formula: C₂₀H₂₃D₅O₂

Color and Shape: Pale Yellow Solid

Molecular weight: 305.47

Ref: 4Z-T-114002

Tretinoin

Controlled Product

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Color and Shape: Neat

Molecular weight: 300.44

Ref: 04-C17608000

Tretinoin

Controlled Product

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Color and Shape: Yellow

Molecular weight: 300.44

Ref: 86-MM1110.00

all-trans-Retinoic Acid

CAS: 302-79-4

Stability Light Sensitive
Applications Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kamm, J.J., et al.: J. Am. Acad. Dermatol., 6, 652 (1982), Warrel, R.P., et al.: Leukemia, 8, 929 (1994), Sasai, Y., et al.: J. Neurol., 249, 41 (2002),

Formula: C₂₀H₂₈O₂

Color and Shape: Yellow

Molecular weight: 300.44

Ref: TR-R250200

all-trans-Retinoic acid

Controlled Product

CAS: 302-79-4

Retinoic acid receptor (RAR) agonist; inhibits melanocyte activity

Formula: C₂₀H₂₈O₂

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 300.44 g/mol

Ref: 3D-FR17921

Tretinoin - Bio-X ™

Controlled Product

CAS: 302-79-4

Tretinoin is a type of retinoic acid that can be used for the treatment of acne. It is a chemical inhibitor that binds to nuclear receptors and leads to an increase in apoptosis. This type of retinoic acid helps with cell detachment and increases shedding thus increasing cell turnover. Tretinoin has been shown to have antibacterial efficacy against Staphylococcus aureus, as well as synergistic effects when combined with other agents, such as cyclic lipopeptide antibiotics and quinolones. Additionally, Tretinoin is used in the research and treatment for promyelocytic leukaemia.

Formula: C₂₀H₂₈O₂

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 300.44 g/mol

Ref: 3D-BR164493

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Purity: 98%

Color and Shape: Solid, Yellow powder

Molecular weight: 300.442

Ref: 10-F317904

all-trans-Retinoic Acid (10,11,14,15-13C4)

Controlled Product

CAS: 302-79-4

Formula: C₄C₁₆H₂₈O₂

Color and Shape: Neat

Molecular weight: 304.406

Ref: TR-R250203

Isotretinoin EP Impurity A

CAS: 302-79-4

Formula: C₂₀H₂₈O₂

Molecular weight: 300.44

Ref: ST-EA-CP-I25001

Tretinoin

CAS: 302-79-4

Vitamins a and their derivatives unmixed

Formula: C₂₀H₂₈O₂

Color and Shape: Yellow Powder

Molecular weight: 300.44

Ref: 45-1674004

Tretinoin

CAS: 302-79-4

Color and Shape: Neat

Ref: 61-FOR1110.00