CAS 30220-46-3: Ingenol

Description:Ingenol, with the CAS number 30220-46-3, is a natural compound derived from the sap of the Euphorbia genus, particularly from the plant Euphorbia peplus. It is classified as a diterpenoid and exhibits a complex structure characterized by a fused ring system. Ingenol has garnered attention for its biological activities, particularly its potential as an anti-cancer agent. It functions through mechanisms such as inducing apoptosis in cancer cells and modulating immune responses. Additionally, ingenol has been studied for its dermatological applications, notably in the treatment of actinic keratosis, a precancerous skin condition. The compound is known for its relatively low toxicity in therapeutic doses, making it a candidate for topical formulations. However, its stability and solubility can vary, which are important considerations in its application. Overall, ingenol represents a significant area of interest in both pharmacology and medicinal chemistry due to its diverse biological effects and potential therapeutic uses.

Formula:C₂₀H₂₈O₅

InChI:InChI=1S/C20H28O5/c1-9-7-19-10(2)5-13-14(18(13,3)4)12(17(19)24)6-11(8-21)16(23)20(19,25)15(9)22/h6-7,10,12-16,21-23,25H,5,8H2,1-4H3/t10-,12+,13-,14+,15+,16-,19+,20-/m1/s1

InChI key:InChIKey=VEBVPUXQAPLADL-POYOOMFHSA-N

SMILES:O=C1C2C=C(CO)C(O)C3(O)C(O)C(=CC13C(C)CC4C2C4(C)C)C

Synonyms:
(1aR,2S,5R,5aR,6S,8aS,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one
(1aR,2S,5R,5aR,6S,8aS,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
(1aR,5R,5aR,6S,9R,10aR)-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)-
1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one, 1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, [1aR-(1aα,2β,5β,5aβ,6β,8aα,9α,10aα)]-
1aalpha,2alpha,5beta,5abeta,6beta,beta,9 alpha, 10,10aalpha-Octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1H-2,8aalpha-methano cyclopenta(a)cyclopropa(e)cyclodecen-11-one
5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-11-one
(-)-Ingenol
Ingenol
See more synonyms

Found 11 products.

Product data	Purity	Price range	Estimated delivery
1H-2,8a-Methanocyclopenta[a]cyclopropa[e]cyclodecen-11-one,1a,2,5,5a,6,9,10,10a-octahydro-5,5a,6-trihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-, (1aR,2S,5R,5aR,6S,8aS,9R,10aR)- REF: IN-DA00I5O8CAS: 30220-46-3	%	65.00 €~562.00 €	Thu 17 Apr 25
Ingenol REF: 7W-GK7087CAS: 30220-46-3	- - -	To inquire	Mon 21 Apr 25
Ingenol REF: 54-BUP08868CAS: 30220-46-3	97.52%	375.00 €~1,839.00 €	Mon 21 Apr 25
Ingenol REF: BP-BP0765CAS: 30220-46-3	95%~99%	104.00 €~680.00 €	Tue 22 Apr 25
Ingenol REF: 3B-I1112CAS: 30220-46-3	>99.0%(HPLC)	86.00 €~274.00 €	Tue 22 Apr 25
Ingenol REF: 4Z-I-062001CAS: 30220-46-3	- - -	To inquire	Thu 24 Apr 25
Ingenol REF: 54-BII3022CAS: 30220-46-3	>99%	190.00 €~1,049.00 €	Thu 24 Apr 25
Ingenol REF: TM-T5S2017CAS: 30220-46-3	99.78% - 99.87%	52.00 €~1,359.00 €	Thu 24 Apr 25
Ingenol REF: 10-M01922CAS: 30220-46-3	>98%	To inquire	Tue 29 Apr 25
Ingenol REF: 3D-FI73952CAS: 30220-46-3	Min. 95%	147.00 €~586.00 €	Mon 28 Apr 25
Ingenol REF: TR-I655795CAS: 30220-46-3	- - -	212.00 €~492.00 €	Wed 28 May 25