CAS 302348-51-2

4-(Hydroxymethyl)benzeneboronic acid pinacol ester

Description:

4-(Hydroxymethyl)benzeneboronic acid pinacol ester, with the CAS number 302348-51-2, is an organoboron compound characterized by the presence of a boronic acid moiety and a hydroxymethyl group attached to a benzene ring. This compound typically exhibits a white to off-white solid appearance and is soluble in organic solvents such as dichloromethane and ethanol, while being less soluble in water. The boronic acid functionality allows for reversible interactions with diols and is significant in various applications, including organic synthesis and medicinal chemistry, particularly in the development of pharmaceuticals and agrochemicals. The pinacol ester formation enhances stability and solubility, making it a useful intermediate in cross-coupling reactions, such as Suzuki-Miyaura coupling. Additionally, the hydroxymethyl group can serve as a handle for further functionalization, expanding its utility in synthetic pathways. Overall, this compound is valuable in both academic research and industrial applications due to its versatile reactivity and functional properties.

Formula: C₁₃H₁₉BO₃

InChI: InChI=1/C13H19BO3/c1-12(2)13(3,4)17-14(16-12)11-7-5-10(9-15)6-8-11/h5-8,15H,9H2,1-4H3

SMILES: CC1(C)C(C)(C)OB(c2ccc(cc2)CO)O1

Synonyms:

• [4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol
• Benzenemethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl Alcohol

CAS: 302348-51-2

Formula: C₁₃H₁₉BO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 234.10

Ref: 3B-T3496

4-(Hydroxymethyl)benzeneboronic acid pinacol ester

CAS: 302348-51-2

4-(Hydroxymethyl)benzeneboronic acid pinacol ester is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product /

Formula: C₁₃H₁₉BO₃

Molecular weight: 234.1

Ref: 02-H51123

Benzenemethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

CAS: 302348-51-2

Formula: C₁₃H₁₉BO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 234.0992

Ref: IN-DA002ZBW

4-Hydroxymethylphenylboronic acid pinacol ester

CAS: 302348-51-2

4-Hydroxymethylphenylboronic acid pinacol ester

Formula: C₁₃H₁₉BO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 234.10g/mol

Ref: 54-OR303456

(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol

CAS: 302348-51-2

Formula: C₁₃H₁₉BO₃

Purity: 95%

Color and Shape: Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 234.1

Ref: 10-F236887

4-HydroxyMethylphenylboronic acid pinacol ester

CAS: 302348-51-2

4-HydroxyMethylphenylboronic acid pinacol ester (4HMPA) is a reactive molecule that binds reversibly to the l1210 leukemia cell line. It can be used as a targeted therapy for cancer, especially in the treatment of fatty acid-related cancers. 4HMPA has been shown to have good specificity and selectivity in cellular microenvironments, with no effect on healthy cells. This drug also has specificities for intestinal cancer cells and can be used as a chemotherapeutic agent. The binding of 4HMPA to the l1210 leukemia cell line is irreversible, which prevents its release from the target cells and allows it to exert its cytotoxic effects. It also inhibits fatty acid synthesis and chloride ion transport, which leads to increased levels of organic solvent in the target cells.

Purity: Min. 95%

Ref: 3D-FH39763