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CAS 3023713-87-0

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  • KBD4466
    Targetmol
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    KBD4466

    CAS:
    KBD4466 is a potent oral inhibitor of TLR7 and TLR8, with IC50 values of 0.9 nM and 2.8 nM, respectively. This compound effectively suppresses the inflammatory cytokines IL-6 and IFN-α. KBD4466 has shown to improve disease progression and increase survival rates in the BXSB/MpJ mouse model of systemic lupus erythematosus (SLE). It is suitable for research into autoimmune diseases.
    Formula:C24H23F3N6O
    Color and Shape:Solid
    Molecular weight:468.47

    Ref: TM-T211376