CymitQuimica logo

CAS 3025180-14-4

:

Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.
  • Microtubulin-IN-1
    Targetmol
    + Info

    Microtubulin-IN-1

    CAS:
    <p>Microtubulin-IN-1 (Compound 8g) is an inhibitor of microtubulin, targeting the colchicine-binding site to disrupt tubulin integrity and induce upregulation of p53 protein expression. It exhibits antiproliferative activity across various cancer cell lines, including NCI-H460, BxPC-3, and HT-29, with IC50 values of 2.4, 1.6, and 2.07 nM, respectively. Additionally, Microtubulin-IN-1 induces cell cycle arrest at the G2/M phase and apoptosis in NCI-H460 cells.</p>
    Formula:C25H21FN4O3
    Color and Shape:Solid
    Molecular weight:444.458

    Ref: TM-T206493