CAS 302781-98-2
:Desfluoro Ezetimibe
CAS:Formula:C24H22FNO3Color and Shape:White To Off-White SolidMolecular weight:391.44Desfluoro-ezetimibe
CAS:Desfluoro-ezetimibe: a defluorinated ezetimibe impurity; a stable, potent cholesterol blocker and Nrf2 activator.Formula:C24H22FNO3Purity:98%Color and Shape:SolidMolecular weight:391.43Desfluoro Ezetimibe
CAS:Controlled ProductImpurity Ezetimibe Desfluoroaniline Analog (USP)
Stability Hygroscopic
Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).
References Anon.: IP.com J., 7, 4 (2007);Formula:C24H22FNO3Color and Shape:White To Off-WhiteMolecular weight:391.43Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS:Lactams, nesoiFormula:C24H22FNO3Color and Shape:White Off-White PowderMolecular weight:391.15837Desfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/mol
