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CAS 3028674-29-2

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  • PRMT5-MTA-IN-3

    CAS:
    <p>PRMT5-MTA-IN-3 (Compound P2A) is an orally active and selective inhibitor of protein arginine methyltransferase 5 (PRMT5). It inhibits the proliferation of MTAP-deficient colorectal cancer HCT-116 cell line with an IC50 value of 5 nM. PRMT5-MTA-IN-3 holds potential for research in cancers, particularly in MTAP-deficient tumors such as colorectal cancer, non-small cell lung cancer, and pancreatic cancer.</p>
    Formula:C19H17F3N6O3
    Color and Shape:Solid
    Molecular weight:434.372