CAS 3029132-46-2

And1 degrader 1

CAS: 3029132-46-2

And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.

Formula: C₂₆H₂₇Cl₂N₃O

Color and Shape: Solid

Molecular weight: 468.42

Ref: TM-T200443