CAS 303-25-3

Cyclizine hydrochloride

Description:

Cyclizine hydrochloride is an antihistamine medication primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness. It belongs to the piperazine class of compounds and functions as an antagonist of the H1 histamine receptor. The substance appears as a white to off-white crystalline powder, which is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Cyclizine hydrochloride exhibits a relatively long duration of action, which is beneficial for managing symptoms over extended periods. Its pharmacological effects include sedation and antiemetic properties, which can be advantageous in clinical settings. However, like many antihistamines, it may cause side effects such as drowsiness, dry mouth, and blurred vision. Caution is advised when using this medication, particularly in individuals with certain medical conditions or those taking other central nervous system depressants. Overall, cyclizine hydrochloride is a valuable therapeutic agent in the management of motion sickness and related disorders.

Formula: C₁₈H₂₃ClN₂

InChI: InChI=1/C18H22N2.ClH/c1-19-12-14-20(15-13-19)18(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18H,12-15H2,1H3;1H

InChI key: InChIKey=UKPBEPCQTDRZSE-UHFFFAOYSA-N

SMILES: C(N1CCN(C)CC1)(C2=CC=CC=C2)C3=CC=CC=C3.Cl

Synonyms:

• 1-(Diphenylmethyl)-4-Methylpiperazine
• 1-Benzhydryl-4-methylpiperazine hydrochloride
• 4-(Diphenylmethyl)-1-Methylpiperazin-1-Ium Chloride
• Cyclizine Hcl
• Cyclizine dihydrochloride
• Marezine hydrochloride
• Marzine
• N-Benzhydryl-N′-methylpiperazine monohydrochloride
• Piperazine, 1-(diphenylmethyl)-4-methyl-, hydrochloride (1:1)
• Piperazine, 1-(diphenylmethyl)-4-methyl-, monohydrochloride
• Cyclizine hydrochloride
• CYCLYZINE HCL
• Echnatol
• 1-(diphenylmethyl)-4-methyl-piperazinhydrochloride
• Collox
• CYCLIZINE HYDROCHLORIDE (200 MG)
• Einecs 206-136-9
• marezinehydrochloride
• Fortravel
• Cyclizini hydrochloridum

Cyclizine Hydrochloride

CAS: 303-25-3

Color and Shape: Neat

Ref: 61-FOR1265.00

CYCLIZINE HYDROCHLORIDE CRS

CAS: 303-25-3

CYCLIZINE HYDROCHLORIDE CRS

Formula: C₁₂H₁₇N₅O

Color and Shape: Crystalline Powder. White. Whitish. Powder.

Molecular weight: 247.2963

Ref: 41-C3090000

Cyclizine hydrochloride

CAS: 303-25-3

Cyclizine hydrochloride

Formula: C₁₈H₂₂N₂HCl

Purity: 99.2%

Color and Shape: White Powder

Molecular weight: 302.15498

Ref: 47-96

Cyclizine Hydrochloride

CAS: 303-25-3

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₈H₂₂N₂·HCI

Color and Shape: White Crystalline Powder

Molecular weight: 406.0906

Ref: 45-1154004

Piperazine, 1-(diphenylmethyl)-4-methyl-, hydrochloride (1:1)

CAS: 303-25-3

Formula: C₁₈H₂₃ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 302.8416

Ref: IN-DA002ZK0

Cyclizine HCl

CAS: 303-25-3

Formula: C₁₈H₂₂N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 266.39 36.46

Ref: 4Z-C-287003

Cyclizine Hydrochloride

Controlled Product

CAS: 303-25-3

Formula: C₁₈H₂₂N₂·ClH

Color and Shape: Neat

Molecular weight: 302.84

Ref: 86-MM1265.00

Cyclizine Hydrochloride

CAS: 303-25-3

Applications Cyclizine is a piperazine derivative with anti-emetic activity that is useful in the prevention and treatment of nausea and vomiting associated with motion sickness. Antiemetic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Kuntzman, R., et al.: J. Pharmacol. Exp. Ther., 158, 332 (1967), Walker, R., et al.: Eur. J. Pharm. Sci., 4, 301 (1996), Dumasia, M., et al.: Xenobiotica, 32, 795 (2002),

Formula: C₁₈H₂₂N₂·ClH

Color and Shape: White Powder

Molecular weight: 302.84

Ref: TR-C987805

Cyclizine hydrochloride

Controlled Product

CAS: 303-25-3

Cyclizine hydrochloride is a histamine H1 receptor antagonist that has been shown to have antioxidative properties. It is used to treat infectious diseases such as influenza, herpes, and malaria. Cyclizine hydrochloride has also been shown to have antimicrobial resistance and can be used for the treatment of autoimmune diseases such as lupus erythematosus. The drug binds to the histamine H1 receptor on the surface of certain cells in the body and blocks the action of histamine, which is a chemical messenger that causes allergic reactions. This binding prevents activation of mast cells or basophils, thereby preventing release of inflammatory mediators such as leukotrienes and prostaglandins. Cyclizine hydrochloride is available in oral tablet form or nasal spray form.

Formula: C₁₈H₂₃ClN₂

Purity: Min 98%

Color and Shape: White Powder

Molecular weight: 302.84 g/mol

Ref: 3D-FC20679

Cyclizine Hydrochloride

CAS: 303-25-3

Formula: C₁₈H₂₂N₂HCl

Molecular weight: 266.39:36.46

Ref: ST-EA-CP-C146001