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CAS 303-26-4

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Norchlorcyclizine

Description:
Norchlorcyclizine, with the CAS number 303-26-4, is a chemical compound that belongs to the class of antihistamines. It is a derivative of cyclizine, which is primarily used for its antiemetic and antihistaminic properties. Norchlorcyclizine exhibits a range of pharmacological effects, including the ability to alleviate symptoms associated with motion sickness and allergies. The compound is characterized by its structural features, which include a piperazine ring and a chlorinated aromatic system, contributing to its biological activity. It is typically administered in various formulations, and its efficacy is attributed to its ability to block histamine H1 receptors. Additionally, Norchlorcyclizine may have sedative effects, making it useful in certain therapeutic contexts. However, like many antihistamines, it may also cause side effects such as drowsiness, dry mouth, and dizziness. Its safety profile and pharmacokinetics are important considerations in clinical use, and it is essential to adhere to recommended dosages to minimize adverse effects.
Formula:C17H19ClN2
InChI:InChI=1/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/p+2/t17-/m0/s1
InChI key:InChIKey=UZKBSZSTDQSMDR-UHFFFAOYSA-N
SMILES:C(C1=CC=C(Cl)C=C1)(C2=CC=CC=C2)N3CCNCC3
Synonyms:
  • (±)-1-(p-Chlorobenzhydryl)piperazine
  • 1-(4-Chloro-α-phenylbenzyl)piperazine
  • 1-(4-Chlorobenzhydryl)-piperizine
  • 1-(4-Chlorophenylmethyl)piperazine
  • 1-(α-Phenyl-4-chlorobenzyl)piperazine
  • 1-[(4-Chlorophenyl) phenylmethyl] piperazine
  • 1-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
  • 1-[(S)-(4-chlorophenyl)(phenyl)methyl]piperazinediium
  • 1-[4-Chlorophenyl) (Phenyl)Methyl] Piperazine
  • 4-(4-Chlorobenzhydryl)piperazine
  • See more synonyms
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