CAS 303-40-2

Fluocortolone caproate

Description:

Fluocortolone caproate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is primarily used in the treatment of various inflammatory and allergic conditions, including skin disorders and certain autoimmune diseases. The compound is characterized by its ability to modulate the immune response and reduce inflammation by inhibiting the release of inflammatory mediators. Fluocortolone caproate is typically administered topically or via injection, depending on the condition being treated. Its chemical structure includes a fluorinated steroid backbone, which enhances its potency and efficacy compared to non-fluorinated corticosteroids. The caproate esterification improves its solubility and absorption, allowing for prolonged therapeutic effects. As with other corticosteroids, potential side effects may include skin thinning, hormonal imbalances, and increased susceptibility to infections, necessitating careful monitoring during treatment. Overall, fluocortolone caproate is an important therapeutic agent in the management of inflammatory conditions, offering significant benefits when used appropriately.

Formula: C₂₈H₃₉FO₅

InChI: InChI=1S/C28H39FO5/c1-5-6-7-8-24(33)34-15-23(32)25-16(2)11-19-18-13-21(29)20-12-17(30)9-10-27(20,3)26(18)22(31)14-28(19,25)4/h9-10,12,16,18-19,21-22,25-26,31H,5-8,11,13-15H2,1-4H3/t16-,18+,19+,21+,22+,25-,26-,27+,28+/m1/s1

InChI key: InChIKey=WHZRCUIISKRTJL-YTZKRAOUSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(C[C@@H](C)[C@@H]2C(COC(CCCCC)=O)=O)[H]

Synonyms:

• (6Alpha,8Xi,9Xi,10Xi,11Beta,13Xi,16Alpha,17Xi)-6-Fluoro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Hexanoate
• (6α,11β,16α)-6-Fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]pregna-1,4-diene-3,20-dione
• 6α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-hexanoate
• 6α-Fluoro-11β-hydroxy-21-hexanoyloxy-16α-methylpregna-1,4-diene-3,20-dione
• Ficoid
• Fluocortolone caproate
• Fluocortolone hexanoate
• Fluocoutolone Hexanoate
• Fluorocortolone 21-caproate
• Hexanoic acid, 21-ester with 6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 6-fluoro-11-hydroxy-16-methyl-21-[(1-oxohexyl)oxy]-, (6α,11β,16α)-
• Pregna-1,4-diene-3,20-dione, 6α-fluoro-11β,21-dihydroxy-16α-methyl-, 21-hexanoate

Fluocortolone 21-Hexanoate

CAS: 303-40-2

Formula: C₂₈H₃₉FO₅

Molecular weight: 474.61

Ref: 4Z-F-071032

Fluocortolone 21-Hexanoate

CAS: 303-40-2

Formula: C₂₈H₃₉FO₅

Molecular weight: 474.61

Ref: ST-EA-CP-F73008

Fluocortolone hexanoate

CAS: 303-40-2

Fluocortolone hexanoate

Formula: C₂₈H₃₉FO₅

Purity: 98.5%

Color and Shape: White

Molecular weight: 474.27815

Ref: 47-161

Fluocortolone 21-hexanoate

Controlled Product

CAS: 303-40-2

Fluocortolone 21-hexanoate is a corticosteroid that is used in the treatment of chronic inflammatory diseases and skin conditions. It has been shown to be effective when used as a monotherapy or in combination with other drugs, including antibiotics and nonsteroidal anti-inflammatory drugs. Fluocortolone 21-hexanoate is given orally or topically to treat skin conditions such as eczema, dermatitis, and psoriasis. This drug has been shown to be effective in treating autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, but may also have some efficacy against t-cell lymphomas. It also has long-term efficacy in the treatment of chronic arthritis. Fluocortolone 21-hexanoate has not shown any drug interactions with other pharmaceuticals, although it may reduce the clearance of drugs metabolized by cytochrome P450 enzymes by inhibiting the activity of these enzymes.

Formula: C₂₈H₃₉FO₅

Purity: Min. 95%

Molecular weight: 474.6 g/mol

Ref: 3D-FF23337

Fluocortolone 21-Hexanoate

Controlled Product

CAS: 303-40-2

Formula: C₂₈H₃₉FO₅

Color and Shape: Neat

Molecular weight: 474.60

Ref: TR-F500510