CAS 303156-68-5

2,4-Octadienoic acid, 8-hydroxy-6-(hydroxymethyl)-4-methyl-, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester, (2E,4E,6S)-

Description:

2,4-Octadienoic acid, 8-hydroxy-6-(hydroxymethyl)-4-methyl-, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester, with the CAS number 303156-68-5, is a complex organic compound characterized by its multi-functional groups and stereochemistry. This substance features a pyran ring, which contributes to its cyclic structure, and multiple double bonds in its octadienoic acid backbone, indicating potential reactivity and unsaturation. The presence of hydroxyl groups suggests it may exhibit hydrogen bonding capabilities, influencing its solubility and interaction with other molecules. The specific stereochemistry, denoted by the (2R,3R) and (1S,3R,5E) configurations, indicates the spatial arrangement of atoms, which is crucial for its biological activity and reactivity. This compound may be of interest in fields such as organic synthesis, pharmaceuticals, or agrochemicals due to its structural complexity and potential functional properties. Its unique characteristics make it a subject of study for applications in various chemical and biological contexts.

Formula: C₂₅H₃₈O₆

Synonyms:

• (a€“)-Rasfonin
• (–)-Rasfonin
• 2,4-Octadienoic acid, 8-hydroxy-6-(hydroxymethyl)-4-methyl-, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester, (2E,4E,6S)-

(-)-Rasfonin

CAS: 303156-68-5

Rasfonin, a fungal metabolite from T. terrophilus, halts mouse splenocyte growth; IC50: 0.7 μg/ml (ConA), 0.5 μg/ml (LPS).

Formula: C₂₅H₃₈O₆

Color and Shape: Solid

Molecular weight: 434.57

Ref: TM-T38038

Rasfonin

CAS: 303156-68-5

Ref: 7W-GW6554

Rasfonin

CAS: 303156-68-5

Rasfonin is a natural product that was found in an extract of the plant Etoac. It has been shown to inhibit the growth of pancreatic cancer cells and have anticancer activity. Rasfonin is structurally similar to the anticancer drug temozolomide, but it does not have any known toxicity. Rasfonin binds to DNA and inhibits transcriptional activation by the nuclear factor-kappa B (NF-κB) pathway. It also induces autophagy, which is important for maintaining cellular homeostasis, preventing tumor formation, and inducing apoptosis. This compound has been shown to inhibit proliferation of normal as well as cancerous cells in vitro and in vivo.

Formula: C₂₅H₃₈O₆

Purity: Min. 95%

Molecular weight: 434.6 g/mol

Ref: 3D-DMA15668