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CAS 3031762-97-4

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  • NA-Ir
    Targetmol
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    NA-Ir

    CAS:
    <p>NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.</p>
    Formula:C49H36F6IrN8O4P
    Color and Shape:Solid
    Molecular weight:1138.04

    Ref: TM-T200615