CAS 3031840-36-2

Acetamide, N-[cis-4-[6-[3-[4-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]-1-piperazinyl]propoxy]-1H-benzimidazol-2-yl]cyclohexyl]-2-[(1H-indol-2-ylmethyl)amino]-

Formula: C₅₀H₅₆ClN₁₁O₃S

Synonyms:

• Acetamide, N-[cis-4-[6-[3-[4-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]-1-piperazinyl]propoxy]-1H-benzimidazol-2-yl]cyclohexyl]-2-[(1H-indol-2-ylmethyl)amino]-

NEP162

CAS: 3031840-36-2

NEP162 is a BRD4 PROTAC degrader with DC50 values of 1.2 μM in SW480 cells and 1.6 μM in U2OS cells. NEP162 exhibits antiproliferative activity, effectively inhibiting tumor growth and inducing apoptosis. It is applicable in research on cancers such as osteosarcoma, colorectal cancer, and non-small cell lung cancer.

Formula: C₅₀H₅₆ClN₁₁O₃S

Color and Shape: Solid

Molecular weight: 926.57

Ref: TM-T211584