CaMKK2-IN-1, identified by its CAS number 3032691-65-6, is a small molecule inhibitor specifically targeting the calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2). This compound is of interest in biochemical research due to its role in modulating cellular signaling pathways associated with metabolism, neuroprotection, and inflammation. The characteristics of CaMKK2-IN-1 include its ability to selectively inhibit CaMKK2 activity, which can influence downstream signaling cascades such as AMP-activated protein kinase (AMPK) pathways. This selectivity makes it a valuable tool for studying the physiological and pathological roles of CaMKK2 in various biological contexts. Additionally, its chemical structure typically features functional groups that enhance its binding affinity and specificity for the target enzyme. As a research compound, it is often utilized in preclinical studies to explore therapeutic potentials in conditions like obesity, diabetes, and neurodegenerative diseases. However, detailed pharmacokinetic and toxicological profiles would be necessary for any potential clinical applications.

CaMKK2-IN-1

3032691-65-6: CaMKK2-IN-1, identified by its CAS number 3032691-65-6, is a small molecule inhibitor specifically targeting the calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2). This compound is of interest in biochemical research due to its role in modulating cellular signaling pathways associated with metabolism, neuroprotection, and inflammation. The characteristics of CaMKK2-IN-1 include its ability to selectively inhibit CaMKK2 activity, which can influence downstream signaling cascades such as AMP-activated protein kinase (AMPK) pathways. This selectivity makes it a valuable tool for studying the physiological and pathological roles of CaMKK2 in various biological contexts. Additionally, its chemical structure typically features functional groups that enhance its binding affinity and specificity for the target enzyme. As a research compound, it is often utilized in preclinical studies to explore therapeutic potentials in conditions like obesity, diabetes, and neurodegenerative diseases. However, detailed pharmacokinetic and toxicological profiles would be necessary for any potential clinical applications.

<p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>

CAS 3032691-65-6

CaMKK2-IN-1

CaMKK2-IN-1

Ref: TM-T208827