AChE-IN-47, identified by its CAS number 3033056-55-9, is a chemical compound that functions as an inhibitor of acetylcholinesterase (AChE), an enzyme responsible for breaking down the neurotransmitter acetylcholine in the synaptic cleft. This inhibition can lead to increased levels of acetylcholine, enhancing cholinergic signaling, which is significant in various neurological contexts. AChE inhibitors are often explored for their potential therapeutic applications in treating conditions such as Alzheimer's disease and other cognitive disorders. The compound's specific characteristics, including its molecular structure, solubility, and pharmacokinetic properties, are essential for understanding its efficacy and safety profile. Additionally, the compound's mechanism of action, potential side effects, and interactions with other drugs are critical factors in its development and application in medicinal chemistry. As with any chemical substance, proper handling and safety measures should be observed, particularly in research and clinical settings.

AChE-IN-47

3033056-55-9: AChE-IN-47, identified by its CAS number 3033056-55-9, is a chemical compound that functions as an inhibitor of acetylcholinesterase (AChE), an enzyme responsible for breaking down the neurotransmitter acetylcholine in the synaptic cleft. This inhibition can lead to increased levels of acetylcholine, enhancing cholinergic signaling, which is significant in various neurological contexts. AChE inhibitors are often explored for their potential therapeutic applications in treating conditions such as Alzheimer's disease and other cognitive disorders. The compound's specific characteristics, including its molecular structure, solubility, and pharmacokinetic properties, are essential for understanding its efficacy and safety profile. Additionally, the compound's mechanism of action, potential side effects, and interactions with other drugs are critical factors in its development and application in medicinal chemistry. As with any chemical substance, proper handling and safety measures should be observed, particularly in research and clinical settings.

<p>AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 μM. It prevents the self-aggregation of β-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS).</p>

CAS 3033056-55-9

AChE-IN-47

AChE-IN-47

Ref: TM-T208738