PKMYT1-IN-2, identified by its CAS number 3033609-84-3, is a small molecule inhibitor that targets the protein kinase MYT1, which plays a crucial role in cell cycle regulation and mitotic progression. This compound is characterized by its ability to selectively inhibit MYT1 activity, thereby influencing cellular processes such as proliferation and apoptosis. The structure of PKMYT1-IN-2 typically includes specific functional groups that enhance its binding affinity to the target kinase, contributing to its efficacy as a potential therapeutic agent in cancer treatment. Additionally, its pharmacokinetic properties, such as solubility, stability, and bioavailability, are essential for determining its suitability for in vivo studies. Research into PKMYT1-IN-2 may also explore its effects on various cancer cell lines, providing insights into its mechanism of action and potential side effects. Overall, PKMYT1-IN-2 represents a promising avenue for developing targeted therapies in oncology, particularly for tumors that exhibit dysregulation of the MYT1 pathway.

PKMYT1-IN-2

3033609-84-3: PKMYT1-IN-2, identified by its CAS number 3033609-84-3, is a small molecule inhibitor that targets the protein kinase MYT1, which plays a crucial role in cell cycle regulation and mitotic progression. This compound is characterized by its ability to selectively inhibit MYT1 activity, thereby influencing cellular processes such as proliferation and apoptosis. The structure of PKMYT1-IN-2 typically includes specific functional groups that enhance its binding affinity to the target kinase, contributing to its efficacy as a potential therapeutic agent in cancer treatment. Additionally, its pharmacokinetic properties, such as solubility, stability, and bioavailability, are essential for determining its suitability for in vivo studies. Research into PKMYT1-IN-2 may also explore its effects on various cancer cell lines, providing insights into its mechanism of action and potential side effects. Overall, PKMYT1-IN-2 represents a promising avenue for developing targeted therapies in oncology, particularly for tumors that exhibit dysregulation of the MYT1 pathway.

<p>PKMYT1-IN-2 (compound 2) serves as a powerful inhibitor of PKMYT1, exhibiting an IC 50 of 5.7 nM. Additionally, it effectively suppresses the proliferation of HCC1569 cells with an IC 50 of 22 nM [1].</p>

CAS 3033609-84-3

PKMYT1-IN-2

PKMYT1-IN-2

Ref: TM-T87219