TDP-43-IN-2 is a small molecule inhibitor that has been studied for its potential therapeutic applications, particularly in the context of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The compound targets the TDP-43 protein, which is implicated in the pathogenesis of these diseases due to its role in RNA metabolism and protein aggregation. Characteristically, TDP-43-IN-2 exhibits specific binding affinity to TDP-43, potentially modulating its function or preventing its pathological aggregation. The compound's structure typically includes functional groups that enhance its solubility and bioavailability, making it suitable for in vivo studies. Additionally, TDP-43-IN-2 has undergone various pharmacological evaluations to assess its efficacy, safety, and mechanism of action. As research continues, understanding the precise biochemical interactions and effects of TDP-43-IN-2 will be crucial for its development as a therapeutic agent in treating TDP-43-related disorders.

TDP-43-IN-2

3033951-93-5: TDP-43-IN-2 is a small molecule inhibitor that has been studied for its potential therapeutic applications, particularly in the context of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The compound targets the TDP-43 protein, which is implicated in the pathogenesis of these diseases due to its role in RNA metabolism and protein aggregation. Characteristically, TDP-43-IN-2 exhibits specific binding affinity to TDP-43, potentially modulating its function or preventing its pathological aggregation. The compound's structure typically includes functional groups that enhance its solubility and bioavailability, making it suitable for in vivo studies. Additionally, TDP-43-IN-2 has undergone various pharmacological evaluations to assess its efficacy, safety, and mechanism of action. As research continues, understanding the precise biochemical interactions and effects of TDP-43-IN-2 will be crucial for its development as a therapeutic agent in treating TDP-43-related disorders.

Thiazolo[5,4-c]pyridin-4(5H)-one

Thiazolo[5,4-c]pyridin-4(5H)-one is a compound used for diagnostic imaging of TDP-43, in PET imaging of neurodegenerative diseases ALS、AD、FTD、LATE.

CAS 3033951-93-5

TDP-43-IN-2

Thiazolo[5,4-c]pyridin-4(5H)-one

Ref: 54-BUP21186

Thiazolo[5,4-c]pyridin-4(5H)-one

Ref: TM-T88035