CAS 3035498-92-8

3,5-Pyrazolidinedione, 4-[(3-bromo-5-nitrophenyl)methylene]-1-(4-methoxyphenyl)-

Description:

3,5-Pyrazolidinedione, 4-[(3-bromo-5-nitrophenyl)methylene]-1-(4-methoxyphenyl)- is a synthetic organic compound characterized by its pyrazolidinedione core, which is a five-membered ring containing two nitrogen atoms and two carbonyl groups. The presence of a methylene bridge connecting the pyrazolidinedione to a substituted phenyl group introduces significant structural complexity. The compound features a 3-bromo-5-nitrophenyl moiety, which contributes to its potential reactivity and biological activity due to the electron-withdrawing effects of the bromine and nitro groups. Additionally, the 4-methoxyphenyl substituent enhances its lipophilicity and may influence its pharmacological properties. This compound may exhibit various biological activities, making it of interest in medicinal chemistry and drug development. Its unique structure suggests potential applications in areas such as anti-inflammatory or analgesic therapies, although specific biological effects would require empirical investigation. As with many synthetic compounds, safety and handling precautions should be observed due to potential toxicity associated with its components.

Formula: C₁₇H₁₂BrN₃O₅

Synonyms:

• 3,5-Pyrazolidinedione, 4-[(3-bromo-5-nitrophenyl)methylene]-1-(4-methoxyphenyl)-

W23-1006

CAS: 3035498-92-8

W23-1006 is a selective covalent ALKBH5 inhibitor. It binds to the ALKBH5 C200 residue with an IC50 value of 3.848 μM. The inhibitory activity of W23-1006 is approximately 30 times stronger than that of FTO and 8 times greater than that of ALKBH3. W23-1006 is applicable for research in triple-negative breast cancer (TNBC).

Formula: C₁₇H₁₂BrN₃O₅

Color and Shape: Solid

Molecular weight: 418.198

Ref: TM-T205034