CAS 3036-82-6

Dipalmitoylphosphatidylserine

Description:

Dipalmitoylphosphatidylserine (DPPS) is a phospholipid that plays a crucial role in cellular membranes, particularly in the structure and function of the lipid bilayer. It is composed of two palmitic acid chains esterified to a glycerol backbone, which is further linked to a phosphatidylserine head group. This amphiphilic nature, with a hydrophilic head and hydrophobic tails, allows DPPS to contribute to membrane fluidity and stability. DPPS is particularly significant in the brain, where it is involved in cell signaling and apoptosis. It is also known for its potential neuroprotective effects and is studied for its implications in cognitive function and neurodegenerative diseases. In laboratory settings, DPPS is often used in the formulation of liposomes and other drug delivery systems due to its biocompatibility and ability to encapsulate therapeutic agents. Additionally, it can serve as a model compound for studying membrane dynamics and interactions in biological systems.

Formula: C₃₈H₇₄NO₁₀P

InChI: InChI=1S/C38H74NO10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45)/t34?,35-/m0/s1

InChI key: InChIKey=KLFKZIQAIPDJCW-HTIIIDOHSA-N

SMILES: C(COP(OC[C@@H](C(O)=O)N)(=O)O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

Synonyms:

• Palmitin, 1,2-di-, dihydrogen phosphate, ester with serine
• 4,6,10-Trioxa-5-phosphahexacosanoic acid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide, (2S)-
• L-Serine, 2,3-bis[(1-oxohexadecyl)oxy]propyl hydrogen phosphate (ester)
• 1,2-Dipalmitoylglycerophosphorylserine
• Dipalmitoylphosphatidylserine

4,6,10-Trioxa-5-phosphahexacosanoic acid, 2-amino-5-hydroxy-11-oxo-8-[(1-oxohexadecyl)oxy]-, 5-oxide, (2S)-

CAS: 3036-82-6

Formula: C₃₈H₇₄NO₁₀P

Molecular weight: 735.9686

Ref: IN-DA002ZVG

1,2-Dipalmitoyl-sn-glycero-3-phosphoserine

CAS: 3036-82-6

1,2-Dipalmitoyl-sn-glycero-3-phosphoserine is a phospholipid that is found in chloroplasts. It has been shown to be an inhibitor of drug transporter proteins and can prevent the transport of drugs into cells. Dipalmitoyl-sn-glycero-3-phosphoserine binds calcium and inhibits the kinetics of the enzyme protein kinase C by binding to its catalytic domain. This phospholipid also functions as a fluorescence probe for basic proteins and cyclic lipopeptides. It has been shown to have pluripotent cell properties, which means it can differentiate into many different types of cells. Dipalmitoyl-sn-glycero-3-phosphoserine has a phase transition temperature of 65°C, which means it melts at this temperature.

Formula: C₃₈H₇₄NO₁₀P

Purity: Min. 95%

Molecular weight: 736 g/mol

Ref: 3D-FD172105