CymitQuimica logo

CAS 3037216-20-6

:

Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 1 products.
  • Tuspetinib dihydrochloride
    Targetmol
    + Info

    Tuspetinib dihydrochloride

    CAS:
    Tuspetinib (HM43239) dihydrochloride is a selective FLT3 inhibitor with oral bioactivity, exhibiting IC50 values of 1.1 nM for FLT3 wild type, 1.8 nM for FLT3ITD mutant type, and 1.0 nM for FLT3D835Y mutant type. As a reversible type I inhibitor, it directly suppresses FLT3 kinase activity and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib dihydrochloride inhibits the proliferation of leukemia cells and induces apoptosis (apoptosis).
    Formula:C29H35Cl3N6
    Color and Shape:Solid
    Molecular weight:573.99

    Ref: TM-T212318