CAS 30377-37-8

6-Amino-1H-purine-2,8(3H,7H)-dione

Description:

6-Amino-1H-purine-2,8(3H,7H)-dione, also known as 6-aminopurine or 6-AP, is a purine derivative characterized by its amino group at the 6-position and a dione structure at the 2 and 8 positions of the purine ring. This compound is a white to off-white crystalline solid that is soluble in water and polar organic solvents. It exhibits basic properties due to the presence of the amino group, which can participate in hydrogen bonding and protonation reactions. 6-Amino-1H-purine-2,8(3H,7H)-dione is of interest in various fields, including biochemistry and molecular biology, as it can act as a purine analog and has potential applications in research related to nucleic acids and cellular processes. Its structural similarity to adenine allows it to interfere with nucleic acid metabolism, making it a subject of study in the context of antiviral and anticancer therapies. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₅H₅N₅O₂

InChI: InChI=1/C5H5N5O2/c6-2-1-3(9-4(11)7-1)10-5(12)8-2/h(H5,6,7,8,9,10,11,12)

InChI key: InChIKey=XFBOJHLYDJZYSP-UHFFFAOYSA-N

SMILES: NC=1C2=C(NC(=O)N2)NC(=O)N1

Synonyms:

• 1H-Purine-2,8(3H,7H)-dione, 6-amino-
• 2,8-Dihydroxyadenine
• 2,8-Dioxyadenine
• 2H-Purine-2,8(3H)-dione, 6-amino-7,9-dihydro-
• 6-Amino-2,8-dihydroxypurine
• 6-Amino-7,9-dihydro-2H-purine-2,8(3H)-dione
• 6-amino-1H-purine-2,8(7H,9H)-dione
• Purine-2,8-diol, 6-amino-
• 6-amino-7,9-dihydro-1H-purine-2,8-dione
• 6-Amino-9H-purine-2,8-diol
• 6-aMino-2,3,7,8-tetrahydro-1H-purine-2,8-dione
• 6-aMino-7H-purine-2,8-diol
• Einecs 250-158-1
• 6-Amino-2,8-dihydroxy-9H-purine
• 6-amino-1H-purine-2,8(3H,7H)-dione

6-amino-7H-purine-2,8-diol

CAS: 30377-37-8

Formula: C₅H₅N₅O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 167.1255

Ref: IN-DA002ZXF

2,8-Dihydroxyadenine

CAS: 30377-37-8

2,8-Dihydroxyadenine causes urinary crystals, kidney stones, and helps diagnose APRT deficiency.

Formula: C₅H₅N₅O₂

Color and Shape: Solid

Molecular weight: 167.128

Ref: TM-T40381

2,8-Dihydroxyadenine

CAS: 30377-37-8

Applications 2,8-Dihydroxyadenine is a derivative of adenine which accumulates in 2,8 dihydroxy-adenine urolithiasis.
References Diculescu, V., et al.: (2007).: Bioelectrochemistry 70, 141 (2007); Taniguchi, et al.: Nucleosides Nucleotides Nucleic Acids 23, 1141 (2004); Wilkinson, H., et al.: Ann. Clin. Biochem., 41, 160 (2004)

Formula: C₅H₅N₅O₂

Color and Shape: White To Beige

Molecular weight: 167.13

Ref: TR-D450105

2,8-Dihydroxyadenine-13C,15N2 (Major)

Controlled Product

CAS: 30377-37-8

Applications 2,8-Dihydroxyadenine-13C,15N2 is the labeled analog of D450105, which is a derivative of adenine which accumulates in 2,8 dihydroxy-adenine urolithiasis.
References Diculescu, V., et al.: (2007).: Bioelectrochemistry 70, 141 (2007); Taniguchi, et al.: Nucleosides Nucleotides Nucleic Acids 23, 1141 (2004); Wilkinson, H., et al.: Ann. Clin. Biochem., 41, 160 (2004)

Formula: C₄₁₃CH₅N₃₁₅N₂O₂

Color and Shape: Neat

Molecular weight: 170.1

Ref: TR-D450107