DDR1-IN-8, with the CAS number 3038810-92-0, is a small molecule inhibitor that targets the discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase involved in various cellular processes, including cell adhesion, migration, and proliferation. This compound is primarily studied for its potential therapeutic applications in cancer and fibrotic diseases, where DDR1 plays a significant role in tumor progression and tissue remodeling. DDR1-IN-8 is characterized by its ability to selectively inhibit DDR1 activity, thereby disrupting the signaling pathways that contribute to pathological conditions. The compound's structure typically includes specific functional groups that enhance its binding affinity to the DDR1 receptor. In vitro and in vivo studies are often conducted to evaluate its efficacy, pharmacokinetics, and safety profile. As research continues, DDR1-IN-8 may provide insights into novel treatment strategies targeting DDR1-related diseases, highlighting the importance of receptor tyrosine kinases in therapeutic development.

DDR1-IN-8

3038810-92-0: DDR1-IN-8, with the CAS number 3038810-92-0, is a small molecule inhibitor that targets the discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase involved in various cellular processes, including cell adhesion, migration, and proliferation. This compound is primarily studied for its potential therapeutic applications in cancer and fibrotic diseases, where DDR1 plays a significant role in tumor progression and tissue remodeling. DDR1-IN-8 is characterized by its ability to selectively inhibit DDR1 activity, thereby disrupting the signaling pathways that contribute to pathological conditions. The compound's structure typically includes specific functional groups that enhance its binding affinity to the DDR1 receptor. In vitro and in vivo studies are often conducted to evaluate its efficacy, pharmacokinetics, and safety profile. As research continues, DDR1-IN-8 may provide insights into novel treatment strategies targeting DDR1-related diseases, highlighting the importance of receptor tyrosine kinases in therapeutic development.

DDR1-IN-8 (compound 7s) is a potent inhibitor of DDR1/2, exhibiting IC50 values of 0.045 μM and 0.126 μM, respectively, and possesses antitumor activity.

CAS 3038810-92-0

DDR1-IN-8

DDR1-IN-8

Ref: TM-T209082