CAS 304-21-2

Harmaline

Description:

Harmaline is a naturally occurring alkaloid primarily found in the seeds of the Peganum harmala plant, commonly known as Syrian rue. It is classified as a beta-carboline and is known for its psychoactive properties. Harmaline exhibits a range of pharmacological effects, including inhibition of monoamine oxidase (MAO), which can lead to increased levels of certain neurotransmitters in the brain. This characteristic makes it of interest in both traditional medicine and modern research, particularly in the context of its potential therapeutic applications. The compound is typically encountered as a white to yellowish crystalline solid and is soluble in alcohol and slightly soluble in water. Harmaline has been studied for its effects on mood, cognition, and its potential role in various neurological conditions. However, it is important to note that harmaline can also produce side effects and may interact with other substances, necessitating caution in its use. As with many psychoactive compounds, further research is needed to fully understand its mechanisms and potential applications.

Formula: C₁₃H₁₄N₂O

InChI: InChI=1S/C13H14N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-4,7,15H,5-6H2,1-2H3

InChI key: InChIKey=RERZNCLIYCABFS-UHFFFAOYSA-N

SMILES: CC=1C2=C(C=3C(N2)=CC(OC)=CC3)CCN1

Synonyms:

• 1-Methyl-7-methoxy-3,4-dihydro-β-carboline
• 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
• 3,4-Dihydroharmine
• 3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
• 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
• 7-methoxy-1-methyl-3,4-dihydro-2H-beta-carboline
• 7-methoxy-1-methyl-4,9-dihydro-3H-beta-carboline
• Harmidine
• Harmine
• NSC 407285
• Harmaline

Harmaline

CAS: 304-21-2

Formula: C₁₃H₁₄N₂O

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 214.27

Ref: 3B-H1237

Harmaline, 98+%

CAS: 304-21-2

CNS stimulant; may act through NMDA receptors. Reversible inhibitor of MAO-A This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Formula: C₁₃H₁₄N₂O

Purity: 98+%

Color and Shape: Crystalline Powder

Molecular weight: 214.27

Ref: 02-J61699

Harmaline

CAS: 304-21-2

Formula: C₁₃H₁₄N₂O

Purity: ≥ 98.0%

Color and Shape: White, off-white or beige to pale brown crystalline powder

Molecular weight: 214.27

Ref: 7W-GP9952

Harmaline

CAS: 304-21-2

Harmaline is a fluorescent psychoactive indole alkaloid from the group of harmala alkaloids and beta-carbolines. It is the reduced hydrogenated form of harmine.

Formula: C₁₃H₁₄N₂O

Purity: 99.57%

Color and Shape: Orthorhombic Bipyramidal Prisms Tablets From Methanol Rhombic Octahedra From Ethanol Solid

Molecular weight: 214.26

Ref: TM-T2797

Harmaline

CAS: 304-21-2

Formula: C₁₃H₁₄N₂O

Purity: 95%~99%

Molecular weight: 214.268

Ref: BP-BP0697

Harmaline

CAS: 304-21-2

Natural alkaloid

Formula: C₁₃H₁₄N₂O

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 214.27

Ref: 5G-89700

3,4-Dihydroharmine

Controlled Product

CAS: 304-21-2

Applications 3,4-Dihydroharmine is a β-Carboline derivative. β-Carbolines are endogenous inhibitors of monoamine oxidase. β-Carbolines are also specific inhibitors of cyclin-dependent kinases;
References Kim, H., et al.: Arch. Biochem. Biophys., 337, 137 (1997); Song, Y., et al.: Bioorg. Med. Chem. Lett., 12, 1129 (2002);

Formula: C₁₃H₁₄N₂O

Color and Shape: Light Beige

Molecular weight: 214.26

Ref: TR-D449718

Harmaline

Controlled Product

CAS: 304-21-2

Harmaline is a natural compound with cox-2 inhibitory activity. It has been shown to decrease the mitochondrial membrane potential and significant cytotoxicity in murine hepatoma cells. Harmaline also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Harmaline can be used as a model system for inhibitor molecules that affect protein phosphatases and kinases, such as protein tyrosine phosphatase 1B (PTP1B). The effects of harmaline on the biological properties of PTP1B have been investigated using molecular docking analysis. This analysis showed that harmaline binds to the ATP binding site in the catalytic domain of PTP1B.

Formula: C₁₃H₁₄N₂O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 214.26 g/mol

Ref: 3D-FH52430

Harmaline pure, 98%

CAS: 304-21-2

Formula: C₁₃H₁₄N₂O

Purity: min. 98 %

Color and Shape: Pale brown, Crystalline powder

Molecular weight: 274.40

Ref: SR-52293

3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-

CAS: 304-21-2

Formula: C₁₃H₁₄N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 214.2631

Ref: IN-DA003005