PF-07957472, identified by its CAS number 3041047-51-9, is a chemical compound that has garnered attention in pharmaceutical research, particularly in the context of its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain protein targets, which may play a role in various biological pathways. The compound's structure typically includes functional groups that contribute to its biological activity and solubility properties. While specific characteristics such as melting point, boiling point, and solubility may vary, compounds of this nature are often evaluated for their pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME). Additionally, PF-07957472 may undergo extensive testing in preclinical and clinical settings to assess its efficacy and safety profile. As with many investigational compounds, detailed information regarding its mechanism of action and therapeutic potential is subject to ongoing research and may evolve as new data becomes available.

PF-07957472

3041047-51-9: PF-07957472, identified by its CAS number 3041047-51-9, is a chemical compound that has garnered attention in pharmaceutical research, particularly in the context of its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain protein targets, which may play a role in various biological pathways. The compound's structure typically includes functional groups that contribute to its biological activity and solubility properties. While specific characteristics such as melting point, boiling point, and solubility may vary, compounds of this nature are often evaluated for their pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME). Additionally, PF-07957472 may undergo extensive testing in preclinical and clinical settings to assess its efficacy and safety profile. As with many investigational compounds, detailed information regarding its mechanism of action and therapeutic potential is subject to ongoing research and may evolve as new data becomes available.

PF-07957472 (Compound 4) is an orally effective inhibitor of the SARS-CoV-2 papain-like protease (PLpro). In NHBE cells infected with SARS-CoV-2, it demonstrated cytopathic effects with an EC50 of 13.9 nM. Additionally, PF-07957472 exhibited antiviral activity in a mouse-adapted COVID-19 infection model.

CAS 3041047-51-9

PF-07957472

PF-07957472

Ref: TM-T200628