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CAS 3043908-63-7

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  • PROTAC pan-KRAS degrader-1
    Targetmol
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    PROTAC pan-KRAS degrader-1

    CAS:
    PROTACpan-KRAS degrader-1 is a pan-KRAS PROTAC degrader that targets multiple KRAS mutants, including G12D, G12C, G12V, and G13D. It effectively degrades the KRAS mutant (G12D) in AGS cells, with a DC50 of 1.1 nM and a Dmax of 95%. This compound can be used in studies of diseases caused by KRAS mutations or amplifications, particularly in cancers such as breast, bladder, and gastric cancer.
    Formula:C63H71F2N13O7S
    Color and Shape:Solid
    Molecular weight:1192.38

    Ref: TM-T211239