CAS 3044-42-6

(11β)-21-(Acetyloxy)-11-hydroxypregna-1,4,16-triene-3,20-dione

Description:

The chemical substance known as (11β)-21-(Acetyloxy)-11-hydroxypregna-1,4,16-triene-3,20-dione, with the CAS number 3044-42-6, is a synthetic steroid compound that belongs to the class of glucocorticoids. It is characterized by its complex steroid structure, which includes multiple fused rings and functional groups such as hydroxyl and acetoxy moieties. This compound exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in the treatment of conditions like asthma, allergies, and autoimmune disorders. The presence of the acetoxy group enhances its lipophilicity, potentially influencing its pharmacokinetics and bioavailability. Additionally, the specific stereochemistry at various positions contributes to its biological activity and receptor binding affinity. As with many steroid derivatives, it is essential to handle this compound with care, considering its potential effects on biological systems and the importance of adhering to safety protocols in laboratory settings.

Formula: C₂₃H₂₈O₅

InChI: InChI=1S/C23H28O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h7-10,16-17,19,21,26H,4-6,11-12H2,1-3H3/t16-,17-,19-,21+,22-,23-/m0/s1

InChI key: InChIKey=ABGUZAVIFZZDDZ-MHYQPVDNSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)C(C(COC(C)=O)=O)=CC4)[H])(CCC1=CC(=O)C=C2)[H])[H]

Synonyms:

• (11Beta)-11-Hydroxy-3,20-Dioxopregna-1,4,16-Trien-21-Yl Acetate
• (11β)-21-(Acetyloxy)-11-hydroxypregna-1,4,16-triene-3,20-dione
• 11Beta,21-Dihydroxypregna-1,4,16-Triene-3,20-Dione 21-Acetate
• 21-Acetoxy-11Β-Hydroxypregna-1,4,16-Triene-3,20-Dione
• Pregna-1,4,16-triene-3,20-dione, 11β,21-dihydroxy-, 21-acetate
• Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-
• 11β,21-Dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate

Deoxyprednisolone-16-ene Acetate (2-((8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate)

CAS: 3044-42-6

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

Formula: C₂₃H₂₈O₅

Color and Shape: White Off-White Solid

Molecular weight: 384.19367

Ref: 45-1A01210

Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-

CAS: 3044-42-6

Formula: C₂₃H₂₈O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 384.4654

Ref: IN-DA00304Z

Budesonide Impurity 3

CAS: 3044-42-6

Formula: C₂₃H₂₈O₅

Color and Shape: White To Off-White Solid

Molecular weight: 384.47

Ref: 4Z-B-0335

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione

Controlled Product

CAS: 3044-42-6

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione is a fine chemical that can be used as a building block for research chemicals or as an intermediate in the synthesis of other compounds. This compound can be used as a reagent or as a speciality chemical to produce high quality and complex compounds. It is also versatile enough to serve as a reaction component or useful scaffold in the synthesis of other valuable chemicals.

Formula: C₂₃H₂₈O₅

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 384.47 g/mol

Ref: 3D-FA175610

21-Acetoxy-11b-hydroxypregna-1,4,16-triene-3,20-dione

Controlled Product

CAS: 3044-42-6

Impurity Budesonide 1,4,16-Triene Impurity
Applications 21-Acetoxy-11β-hydroxypregna-1,4,16-triene-3,20-dione is an intermediate in the synthesis of Budesonide (B689490) related derivatives.
References Ko, D-H., et al.: Med. Chem. Res., 7, 313 (1997);

Formula: C₂₃H₂₈O₅

Color and Shape: Neat

Molecular weight: 384.47

Ref: TR-A165755

Budesonide 1,4,16-Triene Impurity

CAS: 3044-42-6

Formula: C₂₃H₂₈O₅

Molecular weight: 384.47

Ref: ST-EA-CP-B19015