GSK-3β inhibitor 20, identified by its CAS number 3044109-48-7, is a small molecule compound that selectively inhibits glycogen synthase kinase 3 beta (GSK-3β), an important enzyme involved in various cellular processes, including glycogen metabolism, cell signaling, and gene expression. This inhibitor is particularly significant in research related to neurodegenerative diseases, cancer, and diabetes, as GSK-3β is implicated in the pathophysiology of these conditions. The compound typically exhibits a specific binding affinity for the GSK-3β active site, leading to the modulation of its activity. In terms of its physical and chemical properties, GSK-3β inhibitor 20 may possess characteristics such as moderate solubility in organic solvents, stability under physiological conditions, and a defined molecular structure that facilitates its interaction with the target enzyme. Its efficacy and safety profile are often evaluated through in vitro and in vivo studies, making it a valuable tool in pharmacological research and drug development aimed at targeting GSK-3β-related pathways.

GSK-3β inhibitor 20

3044109-48-7: GSK-3β inhibitor 20, identified by its CAS number 3044109-48-7, is a small molecule compound that selectively inhibits glycogen synthase kinase 3 beta (GSK-3β), an important enzyme involved in various cellular processes, including glycogen metabolism, cell signaling, and gene expression. This inhibitor is particularly significant in research related to neurodegenerative diseases, cancer, and diabetes, as GSK-3β is implicated in the pathophysiology of these conditions. The compound typically exhibits a specific binding affinity for the GSK-3β active site, leading to the modulation of its activity. In terms of its physical and chemical properties, GSK-3β inhibitor 20 may possess characteristics such as moderate solubility in organic solvents, stability under physiological conditions, and a defined molecular structure that facilitates its interaction with the target enzyme. Its efficacy and safety profile are often evaluated through in vitro and in vivo studies, making it a valuable tool in pharmacological research and drug development aimed at targeting GSK-3β-related pathways.

<p>GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.</p>

CAS 3044109-48-7

GSK-3β inhibitor 20

GSK-3β inhibitor 20

Ref: TM-T200457