CAS 30459-17-7

1-[4-(Trifluoromethyl)phenyl]piperazine

Description:

1-[4-(Trifluoromethyl)phenyl]piperazine, with the CAS number 30459-17-7, is an organic compound characterized by its piperazine core, which is a six-membered ring containing two nitrogen atoms. The presence of a trifluoromethyl group (-CF3) attached to a phenyl ring significantly influences its chemical properties, enhancing lipophilicity and potentially affecting its biological activity. This compound is typically a solid at room temperature and exhibits moderate solubility in organic solvents. Its structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the piperazine moiety's role in various drug interactions. The trifluoromethyl group is known to impart unique electronic properties, which can enhance the compound's efficacy and selectivity in biological systems. Additionally, the compound may exhibit interesting interactions with biological targets, making it a subject of interest in research related to neuropharmacology and other therapeutic areas. Safety and handling precautions should be observed, as with many fluorinated compounds, due to potential toxicity and environmental concerns.

Formula: C₁₁H₁₃F₃N₂

InChI: InChI=1S/C11H13F3N2/c12-11(13,14)9-1-3-10(4-2-9)16-7-5-15-6-8-16/h1-4,15H,5-8H2

InChI key: InChIKey=IBQMAPSJLHRQPE-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(C=C1)N2CCNCC2

Synonyms:

• 1-(4-Trifluormethylphenyl)-piperazine
• 1-(4-Trifluoromethylphenyl)piperazine
• 1-[4-(Trifluoromethyl)phenyl]piperazine
• 1-[p-(Trifluoromethyl)phenyl]piperazine
• 4-Trifluoromethylphenylpiperazine
• 4-[4-(Trifluoromethyl)Phenyl]Piperazin-1-Ium
• Cd 3-3017
• N-(4-Trifluoromethylphenyl)piperazine
• N-(alpha,alpha,alpha-Trifluoro-p-tolyl)piperazine
• N-(α,α,α-Trifluoro-p-tolyl)piperazine
• Piperazine, 1-(α,α,α-trifluoro-p-tolyl)-

1-(4-Trifluoromethylphenyl)piperazine

CAS: 30459-17-7

Formula: C₁₁H₁₃F₃N₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 230.23

Ref: 3B-T2741

Piperazine, 1-[4-(trifluoromethyl)phenyl]-

CAS: 30459-17-7

Formula: C₁₁H₁₃F₃N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 230.2295

Ref: IN-DA00306V

1-(4-Trifluoromethylphenyl)piperazine

Controlled Product

CAS: 30459-17-7

1-(4-Trifluoromethylphenyl)piperazine is a molecule that belongs to the class of amides. It has been used as an analytical tool for the identification and quantification of neurotransmitters in biological samples. 1-(4-Trifluoromethylphenyl)piperazine exhibits antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, such as Escherichia coli. The antibacterial activity of this compound is due to its ability to inhibit protein synthesis by binding to ribosomes or amide groups on proteins. 1-(4-Trifluoromethylphenyl)piperazine also inhibits the reuptake of monoamines, such as dopamine, serotonin and norepinephrine, which are neurotransmitters responsible for regulating mood and behaviour.
1-(4-Trifluoromethylphenyl)piperazine

Formula: C₁₁H₁₃F₃N₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 230.23 g/mol

Ref: 3D-FT66750