Lipid HTO12, identified by its CAS number 3047222-45-4, is a synthetic lipid compound that is often utilized in biochemical and pharmaceutical research. While specific characteristics may vary, lipids like HTO12 typically exhibit hydrophobic properties, making them essential components of cellular membranes and important in drug delivery systems. They can form micelles or liposomes, which are crucial for encapsulating therapeutic agents. Lipid HTO12 may also possess unique structural features, such as specific fatty acid chains or functional groups, which can influence its behavior in biological systems, including membrane fluidity and permeability. Additionally, it may play a role in various biochemical processes, including signaling pathways and energy storage. The precise applications and characteristics of Lipid HTO12 would depend on its molecular structure and the context in which it is used, such as in formulations for targeted drug delivery or as a model compound in lipid research.

Lipid HTO12 is an ionizable cationic lipid (pKa = 6.432) that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.1 LNPs containing lipid HTO12 and encapsulating adenine base editor mRNA targeting Pcsk9 reduce hepatic Pcsk9 levels in mice at a reduced ionizable lipid/total lipids-to-mRNA ratio than LNPs containing SM-102 (Item No. 33474).WARNING This product is not for human or veterinary use.

Lipid HTO12

3047222-45-4: Lipid HTO12, identified by its CAS number 3047222-45-4, is a synthetic lipid compound that is often utilized in biochemical and pharmaceutical research. While specific characteristics may vary, lipids like HTO12 typically exhibit hydrophobic properties, making them essential components of cellular membranes and important in drug delivery systems. They can form micelles or liposomes, which are crucial for encapsulating therapeutic agents. Lipid HTO12 may also possess unique structural features, such as specific fatty acid chains or functional groups, which can influence its behavior in biological systems, including membrane fluidity and permeability. Additionally, it may play a role in various biochemical processes, including signaling pathways and energy storage. The precise applications and characteristics of Lipid HTO12 would depend on its molecular structure and the context in which it is used, such as in formulations for targeted drug delivery or as a model compound in lipid research.

<p>Lipid HTO12 is an ionizable lipid used for forming lipid nanoparticles (LNP). It facilitates the delivery of siRNA and mRNA.</p>

CAS 3047222-45-4

Lipid HTO12

Lipid HTO12

Ref: TM-TCL-01114