JNK-1-IN-5, with the CAS number 3047794-08-8, is a small molecule inhibitor specifically targeting the c-Jun N-terminal kinase (JNK) pathway, which plays a crucial role in various cellular processes, including stress responses, apoptosis, and inflammation. This compound is characterized by its ability to selectively inhibit JNK1, making it a valuable tool in research related to cancer, neurodegenerative diseases, and other conditions where JNK signaling is implicated. JNK-1-IN-5 is typically studied in vitro and in vivo to assess its efficacy and potential therapeutic applications. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for the JNK enzyme. As with many small molecule inhibitors, understanding its pharmacokinetics, bioavailability, and toxicity profile is essential for evaluating its potential as a therapeutic agent. Researchers often utilize JNK-1-IN-5 to explore the modulation of JNK-related pathways and their effects on cellular behavior, providing insights into disease mechanisms and treatment strategies.

JNK-1-IN-5

3047794-08-8: JNK-1-IN-5, with the CAS number 3047794-08-8, is a small molecule inhibitor specifically targeting the c-Jun N-terminal kinase (JNK) pathway, which plays a crucial role in various cellular processes, including stress responses, apoptosis, and inflammation. This compound is characterized by its ability to selectively inhibit JNK1, making it a valuable tool in research related to cancer, neurodegenerative diseases, and other conditions where JNK signaling is implicated. JNK-1-IN-5 is typically studied in vitro and in vivo to assess its efficacy and potential therapeutic applications. Its chemical structure includes specific functional groups that contribute to its binding affinity and selectivity for the JNK enzyme. As with many small molecule inhibitors, understanding its pharmacokinetics, bioavailability, and toxicity profile is essential for evaluating its potential as a therapeutic agent. Researchers often utilize JNK-1-IN-5 to explore the modulation of JNK-related pathways and their effects on cellular behavior, providing insights into disease mechanisms and treatment strategies.

JNK-1-IN-5 (Compound 14) is a potent JNK1 inhibitor with sub-nanomolar efficacy. It effectively inhibits TGF-β-induced epithelial-mesenchymal transition and shows promise for research targeting JNK1 as an anti-pulmonary fibrosis agent.

CAS 3047794-08-8

JNK-1-IN-5

JNK-1-IN-5

Ref: TM-T204616