c-Fms-IN-15 is a chemical compound that acts as a selective inhibitor of the colony-stimulating factor 1 receptor (CSF1R), which plays a crucial role in the regulation of macrophage function and survival. This compound is characterized by its ability to modulate immune responses, making it of interest in various therapeutic applications, particularly in cancer and inflammatory diseases. The structure of c-Fms-IN-15 typically includes specific functional groups that enhance its binding affinity to the CSF1R, thereby inhibiting its activity. The compound is often studied in the context of drug development, where its pharmacokinetic and pharmacodynamic properties are evaluated to determine efficacy and safety profiles. Additionally, c-Fms-IN-15 may exhibit solubility characteristics that influence its formulation and delivery in biological systems. Overall, its selective inhibition of CSF1R positions c-Fms-IN-15 as a promising candidate for further research in targeted therapies.

c-Fms-IN-15

3047930-25-3: c-Fms-IN-15 is a chemical compound that acts as a selective inhibitor of the colony-stimulating factor 1 receptor (CSF1R), which plays a crucial role in the regulation of macrophage function and survival. This compound is characterized by its ability to modulate immune responses, making it of interest in various therapeutic applications, particularly in cancer and inflammatory diseases. The structure of c-Fms-IN-15 typically includes specific functional groups that enhance its binding affinity to the CSF1R, thereby inhibiting its activity. The compound is often studied in the context of drug development, where its pharmacokinetic and pharmacodynamic properties are evaluated to determine efficacy and safety profiles. Additionally, c-Fms-IN-15 may exhibit solubility characteristics that influence its formulation and delivery in biological systems. Overall, its selective inhibition of CSF1R positions c-Fms-IN-15 as a promising candidate for further research in targeted therapies.

<p>c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with an IC50 of 563 nM.</p>

CAS 3047930-25-3

c-Fms-IN-15

c-Fms-IN-15

Ref: TM-T210059