CAS 30484-77-6: Flunarizine hydrochloride

Description:Flunarizine hydrochloride is a calcium channel blocker primarily used as a medication for the prevention of migraines and the treatment of certain movement disorders, such as vestibular disorders and Parkinson's disease. It is characterized by its ability to inhibit the influx of calcium ions into cells, which helps to reduce neuronal excitability and improve blood flow. The compound is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. Flunarizine is known for its neuroprotective properties and may also exhibit anti-anxiety effects. Its chemical structure includes a diphenylmethyl moiety, contributing to its pharmacological activity. Common side effects may include sedation, weight gain, and gastrointestinal disturbances. Due to its mechanism of action, flunarizine is not recommended for patients with certain cardiovascular conditions. As with any medication, it is essential to use flunarizine under medical supervision, considering potential interactions with other drugs and individual patient health profiles.

Formula:C₂₆H₂₆F₂N₂·2ClH

InChI:InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;

InChI key:InChIKey=RXKMOPXNWTYEHI-RDRKJGRWSA-N

SMILES:Cl.FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)N3CCN(CC=CC=4C=CC=CC4)CC3

Synonyms:
(E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride
1-(Bis(4-Fluorophenyl)Methyl)-4-(3-Phenyl-2-Propenyl)Piperazine Dihydrochloride
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazinediium
Dinaplex
Flugeral
Flunagen
Flunarizine HCl
Flunarizine hydrochloride
Flunarizine, DiHCl
See more synonyms
Flunarl
Fluxarten
Gradient
Issium
Mondus
Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-
Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)
Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-, dihydrochloride
Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-, dihydrochloride, (E)-
R 14950

Found 16 products.

Product data	Purity	Price range	Estimated delivery
Flunarizine dihydrochloride, 99% REF: 02-J62969CAS: 30484-77-6	99%	To inquire	Tue 08 Apr 25
Flunarizine for system suitability CRS REF: 41-Y0002367CAS: 30484-77-6	- - -	115.00 €	Thu 10 Apr 25
Flunarizine dihydrochloride CRS REF: 41-F0189900CAS: 30484-77-6	- - -	115.00 €	Thu 10 Apr 25
Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2) REF: IN-DA0030ACCAS: 30484-77-6	99%	27.00 €~246.00 €	Mon 14 Apr 25
Flunarizine dihydrochloride REF: TM-T0806CAS: 30484-77-6	99.53% - 99.89%	48.00 €~66.00 €	Mon 14 Apr 25
Flunarizine DiHCl REF: 4Z-F-084001CAS: 30484-77-6	- - -	To inquire	Tue 15 Apr 25
Flunarizine hydrochloride REF: 7W-GP9404CAS: 30484-77-6	≤ 0.1%	53.00 €~185.00 €	Tue 15 Apr 25
Flunarizine-d8 DiHCl REF: 4Z-F-084012CAS: 1415586-83-2 30484-77-6	- - -	To inquire	Tue 15 Apr 25
Flunarizine Dihydrochloride REF: 3B-B6727CAS: 30484-77-6	>98.0%(T)(HPLC)	66.00 €	Tue 15 Apr 25
Flunarizine dihydrochloride REF: 04-C13726400CAS: 30484-77-6	- - -	99.00 €	Tue 15 Apr 25
Flunarizine Dihydrochloride REF: 86-MM0175.00CAS: 30484-77-6	- - -	1,523.00 €	Tue 15 Apr 25
Flunarizine dihydrochloride REF: 54-PC900715CAS: 30484-77-6	97% (nmr) (Typical Value in Batch COA)	32.00 €~3,524.00 €	Mon 21 Apr 25
Flunarizine Dihydrochloride REF: TR-F455200CAS: 30484-77-6	- - -	105.00 €~201.00 €	Tue 22 Apr 25
Flunarizine-d8 Dihydrochloride REF: TR-F455202CAS: 1415586-83-2 30484-77-6	- - -	247.00 €~1,478.00 €	Tue 22 Apr 25
Flunarizine dihydrochloride - Bio-X ™ REF: 3D-BF166238CAS: 30484-77-6	Min. 95%	147.00 €	Wed 23 Apr 25
Flunarizine dihydrochloride REF: 3D-FF23332CAS: 30484-77-6	Min. 95%	147.00 €~915.00 €	Mon 05 May 25