CAS 30484-77-6
:Flunarizine hydrochloride
Description:
Flunarizine hydrochloride is a calcium channel blocker primarily used as a medication for the prevention of migraines and the treatment of certain movement disorders, such as vestibular disorders and Parkinson's disease. It is characterized by its ability to inhibit the influx of calcium ions into cells, which helps to reduce neuronal excitability and improve blood flow. The compound is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. Flunarizine is known for its neuroprotective properties and may also exhibit anti-anxiety effects. Its chemical structure includes a diphenylmethyl moiety, contributing to its pharmacological activity. Common side effects may include sedation, weight gain, and gastrointestinal disturbances. Due to its mechanism of action, flunarizine is not recommended for patients with certain cardiovascular conditions. As with any medication, it is essential to use flunarizine under medical supervision, considering potential interactions with other drugs and individual patient health profiles.
Formula:C26H26F2N2·2ClH
InChI:InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;
InChI key:InChIKey=RXKMOPXNWTYEHI-RDRKJGRWSA-N
SMILES:C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4.Cl
Synonyms:- (E)-1-[Bis(4-fluorophenyl)methyl]-4-cinnamylpiperazine dihydrochloride
- 1-(Bis(4-Fluorophenyl)Methyl)-4-(3-Phenyl-2-Propenyl)Piperazine Dihydrochloride
- 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
- 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazinediium
- Dinaplex
- Flugeral
- Flunagen
- Flunarizine HCl
- Flunarizine hydrochloride
- Flunarizine, DiHCl
- Flunarl
- Fluxarten
- Gradient
- Issium
- Mondus
- Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, dihydrochloride, (E)-
- Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)
- Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-, dihydrochloride
- Piperazine, 1-[bis(p-fluorophenyl)methyl]-4-cinnamyl-, dihydrochloride, (E)-
- See more synonyms
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Found 20 products.
Flunarizine dihydrochloride, 99%
CAS:<p>A dual sodium/calcium channel blocker; a cerebral and peripheral vasodilator</p>Formula:C26H26F2N2•2HClPurity:99%Molecular weight:477.4Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)
CAS:Formula:C26H28Cl2F2N2Purity:98%Color and Shape:SolidMolecular weight:477.4167Flunarizine dihydrochloride
CAS:<p>Flunarizine dihydrochloride: a calcium blocker also targeting calmodulin and histamine H1, used for migraine, vertigo, vascular disease, and epilepsy aid.</p>Formula:C26H28Cl2F2N2Purity:99.53% - 99.89%Color and Shape:White Crystalline Powder Odorless And TastelessMolecular weight:477.42Flunarizine hydrochloride
CAS:Formula:C26H26F2N22·HClPurity:≤ 0.1%Color and Shape:White or almost white powderMolecular weight:477.40Flunarizine DiHCl
CAS:Formula:C26H26F2N2·2HClColor and Shape:White To Off-White SolidMolecular weight:404.51 2*36.46Flunarizine dihydrochloride
CAS:<p>Flunarizine dihydrochloride</p>Purity:≥98%Molecular weight:477.42g/molFlunarizine Dihydrochloride
CAS:Formula:C26H26F2N2·2HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:477.42Flunarizine Dihydrochloride
CAS:Controlled ProductFormula:C26H26F2N2ClHColor and Shape:NeatMolecular weight:477.42Flunarizine dihydrochloride
CAS:Controlled ProductFormula:C26H26F2N2ClHColor and Shape:NeatMolecular weight:477.42Flunarizine dihydrochloride
CAS:<p>Flunarizine dihydrochloride</p>Purity:99%Color and Shape: white solidMolecular weight:477.42g/molFlunarizine-d8 Dihydrochloride
CAS:Controlled Product<p>Applications Calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). This is the labeled analog.<br>References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984),<br></p>Formula:C26H20D8Cl2F2N2Color and Shape:NeatMolecular weight:485.47Flunarizine dihydrochloride - Bio-X ™
CAS:<p>Flunarizine is calcium channel blocker that helps to reduce muscle spasms. It shows antimigraine and anticonvulsive activity. This occurs by inhibiting the influx of extracellular calcium through myocardial and vascular membrane pores by physically inhibiting the voltage-dependent calcium channels. Additionally, this drug is a D2 dopamine receptor antagonist.</p>Formula:C26H26F2N2•(HCl)2Purity:Min. 95%Color and Shape:PowderMolecular weight:477.42 g/molPiperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propen-1-yl]-, hydrochloride (1:2)
CAS:Purity:≥99%Molecular weight:477.4200134Flunarizine dihydrochloride
CAS:<p>T-type calcium channel inhibitor</p>Formula:C26H28Cl2F2N2Purity:Min. 95%Color and Shape:PowderMolecular weight:477.42 g/mol
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