CAS 305-01-1

Esculetin

Description:

Esculetin, also known as 6,7-dihydroxycoumarin, is a naturally occurring compound belonging to the coumarin family. It is characterized by its aromatic structure, featuring a benzene ring fused to a lactone. Esculetin is typically a white to pale yellow crystalline solid with a melting point that varies depending on purity. It is soluble in organic solvents such as ethanol and methanol but has limited solubility in water. This compound exhibits various biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties, making it of interest in pharmacological research. Esculetin is also known for its role in plant defense mechanisms and has been studied for potential therapeutic applications, including its effects on cardiovascular health and cancer prevention. Its chemical formula is C9H6O4, and it has a molecular weight of approximately 178.14 g/mol. As a phenolic compound, esculetin can participate in various chemical reactions, including oxidation and complexation with metal ions, further contributing to its biological significance.

Formula: C₉H₆O₄

InChI: InChI=1S/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H

InChI key: InChIKey=ILEDWLMCKZNDJK-UHFFFAOYSA-N

SMILES: OC=1C=C2C(=CC1O)C=CC(=O)O2

Synonyms:

• (2-Chlorophenyl)(Phenyl)Methanone
• 2H-1-Benzopyran-2-one, 6,7-dihydroxy-
• 6,7-Dihidroxi-2-Benzopirona
• 6,7-Dihydroxy-2-Benzopyrone
• 6,7-Dihydroxy-2-benzopyron
• 6,7-Dihydroxy-2H-1-benzopyran-2-one
• 6,7-Dihydroxycoumarin
• Aesculetin
• Asculetine
• Cichorigenin
• Cichoriin aglycon
• Coumarin, 6,7-dihydroxy-
• Esculetin
• Esculetol
• Esculin aglycon

Esculetin

CAS: 305-01-1

Formula: C₉H₆O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Brown to Dark green powder to crystal

Molecular weight: 178.14

Ref: 3B-E0386

Esculetin

CAS: 305-01-1

Esculetin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₉H₆O₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 178.15

Ref: 11-0502

ESCULETIN CRS

CAS: 305-01-1

ESCULETIN CRS

Formula: C₁₃H₉ClO

Color and Shape: Yellow. Powder.

Molecular weight: 216.663

Ref: 41-Y0001611

2H-1-Benzopyran-2-one, 6,7-dihydroxy-

CAS: 305-01-1

Formula: C₉H₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 178.1415

Ref: IN-DA0030E0

Esculetin

CAS: 305-01-1

Esculetin

Purity: ≥98%

Molecular weight: 178.14g/mol

Ref: 54-BUP16540

Esculetin

CAS: 305-01-1

Formula: C₉H₆O₄

Molecular weight: 178.15

Ref: 7W-GE0102

Esculetin

CAS: 305-01-1

Esculetin

Formula: C₉H₆O₄

Purity: > 95 % nmr (Typical Value in Batch COA)

Color and Shape: faint yellow powder

Molecular weight: 178.14g/mol

Ref: 54-BIB6051

Esculetin

CAS: 305-01-1

Formula: C₉H₆O₄

Purity: 95%~99%

Molecular weight: 178.143

Ref: BP-BP0565

Esculetin [Matrix for MALDI-TOF/MS]

CAS: 305-01-1

Formula: C₉H₆O₄

Purity: >99.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 178.14

Ref: 3B-E1287

Esculetin

CAS: 305-01-1

Esculetin: a coumarin from plants with anti-edema, anti-inflammatory, anti-tumor properties; inhibits LOs.

Formula: C₉H₆O₄

Purity: 98.03% - 99.76%

Color and Shape: Yellow Crystalline Powder

Molecular weight: 178.14

Ref: TM-T2798

Esculetin

CAS: 305-01-1

Lactone

Formula: C₉H₆O₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 178.14

Ref: 5G-80449

Esculetin

CAS: 305-01-1

Esculetin is a naturally occurring coumarin compound, which is predominantly derived from various plant sources, such as the bark and leaves of certain trees and shrubs. As a member of the coumarin family, it is characterized by its benzopyrone structure and is often isolated from botanicals through organic solvent extraction methods.

Its mode of action primarily involves its ability to scavenge free radicals and chelate metal ions, contributing to its notable antioxidant capacity. Furthermore, Esculetin exerts anti-inflammatory effects by inhibiting the activity of enzymes such as cyclooxygenase and lipoxygenase, which are integral to the inflammatory pathway.

Common applications of Esculetin are found in scientific research where it is utilized for its potential therapeutic properties. Studies have investigated its role in modulating oxidative stress, its protective effects in neurodegenerative disorders, and its capability to inhibit the proliferation of certain cancer cell lines. Additionally, it serves as a useful biochemical tool in elucidating the pathways of inflammation and oxidative stress within cellular models. Scientists continue to explore its potential as a lead compound in drug discovery and development.

Formula: C₉H₆O₄

Purity: Min. 98.0 Area-%

Molecular weight: 178.15 g/mol

Ref: 3D-E-3400

6,7-Dihydroxy-2H-chromen-2-one

CAS: 305-01-1

Formula: C₉H₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 178.143

Ref: 10-F241171

6,7-Dihydroxycoumarin (Esculetin)

CAS: 305-01-1

Formula: C₉H₆O₄

Color and Shape: Light Yellow

Molecular weight: 178.14

Ref: TR-D446940