CAS 305-33-9: Iproniazid phosphate

Description: Iproniazid phosphate is a chemical compound that serves as a monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. It is the phosphate salt of iproniazid, which was originally developed as an antitubercular agent. The compound is characterized by its ability to inhibit the enzyme monoamine oxidase, leading to increased levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This mechanism of action contributes to its antidepressant effects. Iproniazid phosphate is typically administered in its salt form to enhance solubility and bioavailability. The compound is known for its potential side effects, including hypertensive crises when taken with tyramine-rich foods, necessitating dietary restrictions during treatment. Additionally, it may interact with other medications, requiring careful management by healthcare providers. Overall, iproniazid phosphate is a significant historical compound in psychopharmacology, reflecting the evolution of antidepressant therapies.

Formula: C₉H₁₃N₃O·H₃O₄P

InChI: InChI=1S/C9H13N3O.H3O4P/c1-7(2)11-12-9(13)8-3-5-10-6-4-8;1-5(2,3)4/h3-7,11H,1-2H3,(H,12,13);(H3,1,2,3,4)

InChI key: InChIKey=YPDVTKJXVHYWFY-UHFFFAOYSA-N

SMILES: O=C(NNC(C)C)C=1C=CN=CC1.O=P(O)(O)O

Synonyms:

• 1-Isonicotinyl-2-isopropylhydrazine phosphate
• 1-Isopropyl-2-isonicotinylhydrazine phosphate
• 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, phosphate (1:1)
• Iproniazid dihydrogen phosphate
• Iproniazid phosphate salt
• Iproniazide phosphate
• Iproniazidphosphate
• Isonicotinic acid 2-isopropylhydrazide phosphate
• Isonicotinic acid, 2-isopropylhydrazide, phosphate (1:1)
• Marsilid phosphate
• N'-(1-methylethyl)pyridine-4-carbohydrazide sulfate
• N'-(propan-2-yl)pyridine-4-carbohydrazide
• N'-(propan-2-yl)pyridine-4-carbohydrazide phosphate (1:1)
• NSC 81850
• Iproniazid phosphate

Iproniazid Phosphate

CAS: 305-33-9

Iproniazid Phosphate is a non-selective, irreversible monoamine oxidase inhibitor (MAOI).

• Formula: C₉H₁₃N₃O·H₃PO₄
• Purity: 98.69% - 99.87%
• Color and Shape: Solid
• Molecular weight: 277.21

4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, phosphate (1:1)

CAS: 305-33-9

• Formula: C₉H₁₆N₃O₅P
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 277.2142

Iproniazid Phosphate

CAS: 305-33-9

• Formula: C₉H₁₃N₃O·H₃O₄P
• Color and Shape: Neat
• Molecular weight: 277.21

N'-Isopropylisonicotinohydrazide phosphate

CAS: 305-33-9

• Purity: 95.0%
• Color and Shape: Solid, solid
• Molecular weight: 277.2170104980469

Iproniazid phosphate

CAS: 305-33-9

Iproniazid phosphate is a drug that inhibits the enzyme acetylcholinesterase, which breaks down the neurotransmitter …

• Formula: C₉H₁₆N₃O₅P
• Purity: Min. 95%
• Molecular weight: 277.21 g/mol