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CAS 305-33-9

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Iproniazid phosphate

Description:
Iproniazid phosphate is a chemical compound that serves as a monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. It is the phosphate salt of iproniazid, which was originally developed as an antitubercular agent. The compound is characterized by its ability to inhibit the enzyme monoamine oxidase, leading to increased levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain. This mechanism of action contributes to its antidepressant effects. Iproniazid phosphate is typically administered in its salt form to enhance solubility and bioavailability. The compound is known for its potential side effects, including hypertensive crises when taken with tyramine-rich foods, necessitating dietary restrictions during treatment. Additionally, it may interact with other medications, requiring careful management by healthcare providers. Overall, iproniazid phosphate is a significant historical compound in psychopharmacology, reflecting the evolution of antidepressant therapies.
Formula:C9H16N3O5P
InChI:InChI=1/C9H13N3O.H2O4S/c1-7(2)11-12-9(13)8-3-5-10-6-4-8;1-5(2,3)4/h3-7,11H,1-2H3,(H,12,13);(H2,1,2,3,4)
InChI key:InChIKey=YPDVTKJXVHYWFY-UHFFFAOYSA-N
SMILES:P(=O)(O)(O)O.C(NNC(C)C)(=O)C=1C=CN=CC1
Synonyms:
  • 1-Isonicotinyl-2-isopropylhydrazine phosphate
  • 1-Isopropyl-2-isonicotinylhydrazine phosphate
  • 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, phosphate (1:1)
  • Iproniazid dihydrogen phosphate
  • Iproniazid phosphate salt
  • Iproniazide phosphate
  • Iproniazidphosphate
  • Isonicotinic acid 2-isopropylhydrazide phosphate
  • Isonicotinic acid, 2-isopropylhydrazide, phosphate (1:1)
  • Marsilid phosphate
  • See more synonyms
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