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CAS 3051650-00-8

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  • W4275
    Targetmol
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    W4275

    CAS:
    <p>W4275 (Compound 42) is a selective NSD2 inhibitor with oral activity and an IC50 of 17 nM. It exhibits antiproliferative activity, with an IC50 of 230 nM against RS411 cells, and significantly inhibits tumor growth in an RS411 tumor xenograft model. Pharmacokinetic analysis in mice shows that W4275 has a favorable oral bioavailability (F is 27.34%). W4275 holds potential for use in cancer research.</p>
    Formula:C25H36N6O3
    Color and Shape:Solid
    Molecular weight:468.59

    Ref: TM-T200598