
CAS 3052804-28-8
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Antibacterial agent 256
CAS:<p>Antibacterialagent 256 (Compound C09) is an inhibitor of Type I signal peptidase (SPase I). It targets Gram-positive bacteria, effectively inhibiting S. aureus ATCC 29213, E. faecium QF31, E. faecalis SF23-1, and S. suis P1/7, with MIC values ranging from 1-16 μg/mL. In cancer cells HEp-2 and Caco-2, Antibacterialagent 256 exhibits cytotoxicity with CC50 values of 14.65 μg/mL and 21.93 μg/mL, respectively. Additionally, it shows hemolytic activity on mouse red blood cells with an HC50 of 13.29 μg/mL and can improve MRSA skin infections in mouse models.</p>Formula:C27H19ClF3NO2SColor and Shape:SolidMolecular weight:513.96
