CAS 305335-31-3

L-Histidine,N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-

Description:

L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]- is a chemical compound that features a histidine backbone modified with specific side chains. This compound is characterized by the presence of a carboxylic acid group and a branched alkyl chain, which contributes to its potential biological activity. The incorporation of a 3,5-dichlorophenyl group suggests that it may exhibit unique interactions with biological targets, possibly influencing its pharmacological properties. As a derivative of histidine, it retains the amino acid's basic properties, including the ability to participate in hydrogen bonding and act as a zwitterion under physiological conditions. The presence of chlorine substituents on the phenyl ring can enhance lipophilicity and alter the compound's reactivity. Overall, this compound may be of interest in medicinal chemistry and biochemistry, particularly in the development of therapeutic agents or as a biochemical probe, although specific biological activities and applications would require further investigation.

Formula: C₁₉H₂₃Cl₂N₃O₄

MLN-4760

CAS: 305335-31-3

MLN-4760 is a human ACE2 inhibitor with an IC50 of 0.44 nM, highly selective (>5000-fold) over testicular ACE and CPDA.

Formula: C₁₉H₂₃Cl₂N₃O₄

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 428.31

Ref: TM-T16116

((S)-1-Carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine

CAS: 305335-31-3

Formula: C₁₉H₂₃Cl₂N₃O₄

Purity: 99%

Molecular weight: 428.3096

Ref: IN-DA01JIYK

MLN-4760

CAS: 305335-31-3

MLN-4760

Purity: ≥98%

Molecular weight: 428.31g/mol

Ref: 54-BUP01750

MLN-4760

CAS: 305335-31-3

MLN-4760 is a new chemical entity with potent inhibitory effects against the angiotensin II type 1 receptor. It also has an inhibitory effect on the renin-angiotensin system, which is involved in regulating blood pressure and heart function. MLN-4760 binds to the angiotensin II type 1 receptor and blocks its interaction with angiotensin II, leading to reduced cardiac hypertrophy, heart failure, and death in animal models of cardiac hypertrophy. In addition, MLN-4760 has been shown to have antitumor properties in vitro and in vivo. This compound is a natural product that was isolated from Chinese herbs used for centuries for their therapeutic benefits.

Formula: C₁₉H₂₃Cl₂N₃O₄

Purity: Min. 95%

Molecular weight: 428.3 g/mol

Ref: 3D-FMA33531